Advanced maternal age and adverse pregnancy outcomes: A systematic review and meta-analysis

SC Lean, H Derricott, RL Jones, AEP Heazell - PloS one, 2017 - journals.plos.org
Background Advanced maternal age (AMA;≥ 35 years) is an increasing trend and is
reported to be associated with various pregnancy complications. Objective To determine the …

Endothelial dysfunction and vascular disease–a 30th anniversary update

PM Vanhoutte, H Shimokawa, M Feletou… - Acta …, 2017 - Wiley Online Library
The endothelium can evoke relaxations of the underlying vascular smooth muscle, by
releasing vasodilator substances. The best‐characterized endothelium‐derived relaxing …

[HTML][HTML] Pregnancy outcomes in women of advanced maternal age: a retrospective cohort study from China

D Shan, PY Qiu, YX Wu, Q Chen, AL Li, S Ramadoss… - Scientific reports, 2018 - nature.com
This retrospective cohort study attempts to investigate pregnancy complications and adverse
pregnancy outcomes in women of advanced maternal age (AMA). Data were extracted from …

Effect of the interaction between advanced maternal age and pre-pregnancy BMI on pre-eclampsia and GDM in Central China

M Sun, M Luo, T Wang, J Wei, S Zhang, J Shu… - BMJ Open Diabetes …, 2023 - drc.bmj.com
Introduction To investigate the independent and combined effects of advanced maternal age
and pre-pregnancy body mass index (BMI) on the risk of pre-eclampsia and gestational …

[HTML][HTML] Unveiling uterine aging: much more to learn

Y Wu, M Li, J Zhang, S Wang - Ageing Research Reviews, 2023 - Elsevier
Uterine aging is an important factor that impacts fertility, reproductive health, and uterus-
related diseases; however, it remains poorly explored. Functionally, these disturbances …

Placental dysfunction underlies increased risk of fetal growth restriction and stillbirth in advanced maternal age women

SC Lean, AEP Heazell, MR Dilworth, TA Mills… - Scientific reports, 2017 - nature.com
Pregnancies in women of advanced maternal age (AMA) are susceptible to fetal growth
restriction (FGR) and stillbirth. We hypothesised that maternal ageing is associated with …

Advanced maternal age and the impact on maternal and offspring cardiovascular health

CLM Cooke, ST Davidge - American Journal of Physiology …, 2019 - journals.physiology.org
Delaying pregnancy, which is on the rise, may increase the risk of cardiovascular disease in
both women and their children. The physiological mechanisms that lead to these effects are …

Reduction in regulatory T cells in early pregnancy causes uterine artery dysfunction in mice

AS Care, SL Bourque, JS Morton, EP Hjartarson… - …, 2018 - Am Heart Assoc
Preeclampsia, fetal growth restriction, and miscarriage remain important causes of maternal
and perinatal morbidity and mortality. These complications are associated with reduced …

[HTML][HTML] Maternal perinatal outcomes related to advanced maternal age in preeclampsia pregnant women

BD Tyas, P Lestari, MIA Akbar - Journal of family & reproductive …, 2019 - ncbi.nlm.nih.gov
Objective: This study aims to analyze the effect of advanced maternal age (> 35 years old) in
maternal and perinatal outcomes of preeclampsia women. Materials and methods: This is a …

Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum

HE Collins, BT Alexander, AS Care… - American Journal …, 2024 - journals.physiology.org
Maternal mortality rates are at an all-time high across the world and are set to increase in
subsequent years. Cardiovascular disease is the leading cause of death during pregnancy …