The dorsolateral prefrontal cortex (DLPFC) is a functionally and structurally heterogeneous
region and a key node of several brain networks, implicated in cognitive, affective, and …

Despite over two decades of neuroimaging research, a unanimous definition of the pattern
of structural variation associated with autism spectrum disorder (ASD) has yet to be found …

Pain is a highly complex and individual experience with biological, psychological and social
(biopsychosocial) contributions. Pain is associated with activity within the nervous system …

Objectives The aetiology of primary chronic pain syndromes (CPS) is highly disputed. We
performed a systematic review and meta-analysis aiming to assess differences in circulating …

Ovarian hormones play an important role in pain perception, and are responsible, at least in
part, for the pain threshold differences between the sexes. Modulation of pain and its …

Chronic pain and cognitive impairment are prevalent geriatric syndromes in the population
of older adults, and they are the main cause of disability in people over sixty-five years of …

Chronic pain is often measured with a severity score that overlooks its spatial distribution
across the body. This widespread pain is believed to be a marker of centralization, a central …

Acutely, pain is protective. It promotes escape from, and future avoidance of, noxious stimuli
through strong and often lifetime associative memories. However, with persistent acute pain …

Magnetic resonance imaging (MRI) of the brain combined with voxel-based morphometry
(VBM) revealed changes in gray matter volume (GMV) in various disorders. However, the …

Fibromyalgia (FM) is a complex syndrome characterised by chronic pain, fatigue and
functional symptoms. Widespread pain is often its most typical feature, whereas other …