The break of the epithelial barrier of gingiva has been a subject of minor interest, albeit
playing a key role in periodontal pathology, transitory bacteraemia, and subsequent …

Kupffer cells (KCs) are localized in liver sinusoids but extend pseudopods to parenchymal
cells to maintain their identity and serve as the body's central bacterial filter. Liver cirrhosis …

The liver is a vital metabolic organ that also performs important immune-regulatory functions.
In the context of infections, the liver represents a target site for various pathogens, while also …

Staphylococcus aureus (S. aureus) is a pathobiont of humans as well as a multitude of
animal species. The high prevalence of multi-resistant and more virulent strains of S. aureus …

Liver transplantation (LT) stands as the gold standard for treating end‐stage liver disease
and hepatocellular carcinoma, yet postoperative complications continue to impact survival …

In adults, liver-resident macrophages, or Kupffer cells (KCs), reside in the sinusoids and
sterilize circulating blood by capturing rapidly flowing microbes. We developed quantitative …

Donor infection affects organ utilization, especially the infections by multidrug-resistant
bacteria, which may have disastrous outcomes. We established a rat model, inoculated with …

Hepatic macrophages have been recognized as primary sensors and responders in liver
inflammation. By processing host or exogenous biochemical signals, including microbial …

Leukocytes are among the most mobile and versatile cells that have many essential
functions in homeostasis and survival. Especially cells from the innate immune system, ie …

Allogeneic grafts are vulnerable to the attack launched by host alloreactive T cells, which
accounts primarily for allograft failure in the clinic. Conventional pharmacological …