IL-6 and IL-8: an overview of their roles in healthy and pathological pregnancies

A Vilotić, M Nacka-Aleksić, A Pirković… - International journal of …, 2022 - mdpi.com
Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

Placental tissues as biomaterials in regenerative medicine

A Roy, M Mantay, C Brannan… - BioMed Research …, 2022 - Wiley Online Library
Placental tissues encompass all the tissues which support fetal development, including the
placenta, placental membrane, umbilical cord, and amniotic fluid. Since the 1990s there has …

Association of pro‐and anti‐inflammatory cytokines in preeclampsia

R Aggarwal, AK Jain, P Mittal, M Kohli… - Journal of clinical …, 2019 - Wiley Online Library
Introduction The pro‐and anti‐inflammatory cytokines play crucial role in the development
and functions of placenta. Any changes in these cytokines may be associated with many …

Interleukin-6 in pregnancy and gestational disorders

JR Prins, N Gomez-Lopez, SA Robertson - Journal of reproductive …, 2012 - Elsevier
IL6 is a multifunctional cytokine with pivotal roles in the inflammatory response and in
directing T cell differentiation in adaptive immunity. IL6 is widely expressed in the female …

Cytokines, prostaglandins and parturition—a review

JA Keelan, M Blumenstein, RJA Helliwell, TA Sato… - Placenta, 2003 - Elsevier
The elaboration of cytokines, chemokines and immunomodulatory proteins in the placenta
and gestational membranes has been extensively investigated in the context of both normal …

[HTML][HTML] Cytokines as key players in the pathophysiology of preeclampsia

R Raghupathy - Medical Principles and Practice, 2013 - karger.com
Preeclampsia (PE) is an important, common, and dangerous complication of pregnancy; it
causes maternal and perinatal illness and is responsible for a high proportion of maternal …

[PDF][PDF] The human placenta in gestational diabetes mellitus: the insulin and cytokine network

G Desoye, S Hauguel-de Mouzon - Diabetes care, 2007 - mundialsiglo21.com
The placenta is a complex fetal organ that fulfills pleiotropic roles during fetal growth. It
separates the maternal and fetal circulation, with which it is in contact through different …

Role of leptin as a link between metabolism and the immune system

A Pérez-Pérez, T Vilariño-García… - Cytokine & growth factor …, 2017 - Elsevier
Leptin is an adipocyte-derived hormone not only with an important role in the central control
of energy metabolism, but also with many pleiotropic effects in different physiological …

Inflammation in reproductive disorders

G Weiss, LT Goldsmith, RN Taylor, D Bellet… - Reproductive …, 2009 - Springer
Inflammatory disorders account for a significant percentage of gynecologic disease,
particularly in reproductive age women. Inflammation is a basic method by which we …

Cytokines of the placenta and extra-placental membranes: roles and regulation during human pregnancy and parturition

JM Bowen, L Chamley, JA Keelan, MD Mitchell - Placenta, 2002 - Elsevier
In an earlier, companion, review, we concluded that cytokines produced by the placenta and
associated membranes are likely to be involved in control of the processes of implantation …