Opioids and public health: the prescription opioid ecosystem and need for improved management

ED Kharasch, JD Clark, JM Adams - Anesthesiology, 2022 - pmc.ncbi.nlm.nih.gov
While US opioid prescribing has decreased 38% in the past decade, opioid deaths have
increased 300%. This opioid paradox is poorly recognized. Current approaches to opioid …

The opioid epidemic in pediatrics: a 2020 update

M Yaster, PP McNaull, PJ Davis - Current Opinion in …, 2020 - journals.lww.com
We describe the historical use of opioids and the scope of the current opioid crisis, review
the differences between dependence and addiction, and the private and public sectors …

Cost and outcomes of intercostal nerve cryoablation versus thoracic epidural following the Nuss procedure

RAP Holguin, N DeAngelo, A Sinha, C Shen… - Journal of pediatric …, 2023 - Elsevier
Background Pectus excavatum is the most common congenital chest wall abnormality, with
the Nuss procedure being the most commonly performed repair. Pain control is the …

Association of opioid prescription initiation during adolescence and young adulthood with subsequent substance-related morbidity

PD Quinn, KL Fine, ME Rickert, AC Sujan… - JAMA …, 2020 - jamanetwork.com
Importance Concerns about adverse outcomes associated with opioid analgesic
prescription have led to major guideline and policy changes. Substantial uncertainty …

The utility and accuracy of ChatGPT in providing post-operative instructions following tonsillectomy: A pilot study

S Dhar, D Kothari, M Vasquez, T Clarke… - International Journal of …, 2024 - Elsevier
Objective To investigate the utility of answers generated by ChatGPT, a large language
model, to common questions parents have for their children following tonsillectomy. Methods …

We need to talk: the urgent conversation on chronic pain, mental health, prescribing patterns and the opioid crisis

M Battaglia, CB Groenewald… - Journal of …, 2023 - journals.sagepub.com
The opioid crisis' pathways from first exposure onwards to eventual illnesses and fatalities
are multiple, intertwined and difficult to dissect. Here, we offer a multidisciplinary appraisal of …

Exploring non-pharmacological management among anesthesia providers to reduce preoperative distress in children

R Bizzio, R Cianelli, N Villegas, M Hooshmand… - Journal of pediatric …, 2020 - Elsevier
Preparation for surgery with the induction of general anesthesia is one of the most stressful
events that a child can experience. It produces several threats to the child, including physical …

Ketamine prolonged infusions in the pediatric intensive care unit: a tertiary-care single-center analysis

F Sperotto, I Giaretta, MC Mondardini… - The Journal of …, 2020 - meridian.allenpress.com
OBJECTIVE Ketamine is commonly used as an anesthetic and analgesic agent for
procedural sedation, but there is little evidence on its current use as a prolonged continuous …

Paternal morphine alters offspring circulating beta-endorphin and corticosterone responses to oxycodone and cocaine

SB Isgate, KE Budge, EM Byrnes, FM Vassoler - Neuropharmacology, 2025 - Elsevier
Background The opioid epidemic is leading to increased opioid use in adolescent
populations. A growing body of evidence suggests that taking opioids during adolescence …

Evidence for a multimodal pain management regimen in reduction of postoperative opioid use in pediatric patients receiving posterior spinal fusion for adolescent …

RW Collis, T Dry, HE Ray, N Grundlingh, G Chan… - Spine, 2023 - journals.lww.com
Study Design: Retrospective cohort study. Objective: This project aims to evaluate the
relationship between increased use of intraoperative nonopioid analgesics, muscle relaxers …