The Multivalent Role of Fibronectin-Binding Proteins A and B (FnBPA and FnBPB) of Staphylococcus aureus in Host Infections

P Speziale, G Pietrocola - Frontiers in microbiology, 2020 - frontiersin.org
Staphylococcus aureus, one of the most important human pathogens, is the causative agent
of several infectious diseases including sepsis, pneumonia, osteomyelitis, endocarditis and …

AFM in cellular and molecular microbiology

YF Dufrêne, A Viljoen, J Mignolet… - Cellular …, 2021 - Wiley Online Library
The unique capabilities of the atomic force microscope (AFM), including super‐resolution
imaging, piconewton force‐sensitivity, nanomanipulation and ability to work under …

Zinc-dependent mechanical properties of Staphylococcus aureus biofilm-forming surface protein SasG

C Formosa-Dague, P Speziale… - Proceedings of the …, 2016 - National Acad Sciences
Staphylococcus aureus surface protein SasG promotes cell–cell adhesion during the
accumulation phase of biofilm formation, but the molecular basis of this interaction remains …

Atomic force microscopy in microbiology: new structural and functional insights into the microbial cell surface

YF Dufrêne - MBio, 2014 - Am Soc Microbiol
Microbial cells sense and respond to their environment using their surface constituents.
Therefore, understanding the assembly and biophysical properties of cell surface molecules …

Staphylococcus aureus fibronectin-binding protein A mediates cell-cell adhesion through low-affinity homophilic bonds

P Herman-Bausier, S El-Kirat-Chatel, TJ Foster… - MBio, 2015 - Am Soc Microbiol
Staphylococcus aureus is an important opportunistic pathogen which is a leading cause of
biofilm-associated infections on indwelling medical devices. The cell surface-located …

The binding force of the staphylococcal adhesin SdrG is remarkably strong

P Herman, S El‐Kirat‐Chatel, A Beaussart… - Molecular …, 2014 - Wiley Online Library
SdrG is a cell surface adhesin from S taphylococcus epidermidis which binds to the blood
plasma protein fibrinogen (Fg). Ligand binding follows a 'dock, lock and latch'model …

Stuck in the middle: fibronectin-binding proteins in gram-positive bacteria

JP Hymes, TR Klaenhammer - Frontiers in microbiology, 2016 - frontiersin.org
Fibronectin is a multidomain glycoprotein found ubiquitously in human body fluids and
extracellular matrices of a variety of cell types from all human tissues and organs, including …

Mechanical Forces Guiding Staphylococcus aureus Cellular Invasion

V Prystopiuk, C Feuillie, P Herman-Bausier, F Viela… - Acs Nano, 2018 - ACS Publications
Staphylococcus aureus can invade various types of mammalian cells, thereby enabling it to
evade host immune defenses and antibiotics. The current model for cellular invasion …

saeRS and sarA Act Synergistically to Repress Protease Production and Promote Biofilm Formation in Staphylococcus aureus

LN Mrak, AK Zielinska, KE Beenken, IN Mrak… - PloS one, 2012 - journals.plos.org
Mutation of the staphylococcal accessory regulator (sarA) limits biofilm formation in diverse
strains of Staphylococcus aureus, but there are exceptions. One of these is the commonly …

[PDF][PDF] Recent developments for Staphylococcus aureus vaccines: clinical and basic science challenges

RA Proctor - Eur Cell Mater, 2015 - ecmjournal.org
Bacterial vaccines have made dramatic impacts upon morbidity and mortality caused by a
number of common pathogens, but a vaccine to prevent Staphylococcus aureus infections …