Delirium
Delirium, a syndrome characterized by an acute change in attention, awareness and
cognition, is caused by a medical condition that cannot be better explained by a pre-existing …
cognition, is caused by a medical condition that cannot be better explained by a pre-existing …
The inter-relationship between delirium and dementia: the importance of delirium prevention
Delirium and dementia are two frequent causes of cognitive impairment among older adults
and have a distinct, complex and interconnected relationship. Delirium is an acute …
and have a distinct, complex and interconnected relationship. Delirium is an acute …
Long-term cognitive impairment after acute respiratory distress syndrome: a review of clinical impact and pathophysiological mechanisms
Acute respiratory distress syndrome (ARDS) survivors experience a high prevalence of
cognitive impairment with concomitantly impaired functional status and quality of life, often …
cognitive impairment with concomitantly impaired functional status and quality of life, often …
Cerebral dysfunctions caused by sepsis during ageing
T Manabe, MT Heneka - Nature Reviews Immunology, 2022 - nature.com
Systemic inflammation elicited by sepsis can induce an acute cerebral dysfunction known as
sepsis-associated encephalopathy (SAE). Recent evidence suggests that SAE is common …
sepsis-associated encephalopathy (SAE). Recent evidence suggests that SAE is common …
The interface between delirium and dementia in elderly adults
Delirium and dementia are two of the most common causes of cognitive impairment in older
populations, yet their interrelation remains poorly understood. Previous studies have shown …
populations, yet their interrelation remains poorly understood. Previous studies have shown …
Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL‐1β drives amplified responses in primed astrocytes and neuronal network …
AB Lopez‐Rodriguez, E Hennessy… - Alzheimer's & …, 2021 - Wiley Online Library
Neuroinflammation contributes to Alzheimer's disease (AD) progression. Secondary
inflammatory insults trigger delirium and can accelerate cognitive decline. Individual cellular …
inflammatory insults trigger delirium and can accelerate cognitive decline. Individual cellular …
The consistent burden in published estimates of delirium occurrence in medical inpatients over four decades: a systematic review and meta-analysis study
Introduction Delirium is associated with a wide range of adverse patient safety outcomes, yet
it remains consistently under-diagnosed. We undertook a systematic review of studies …
it remains consistently under-diagnosed. We undertook a systematic review of studies …
Update of the European Society of Anaesthesiology and Intensive Care Medicine evidence-based and consensus-based guideline on postoperative delirium in adult …
C Aldecoa, G Bettelli, F Bilotta… - European Journal of …, 2024 - journals.lww.com
Update of the European Society of Anaesthesiology and Intens... : European Journal of
Anaesthesiology | EJA Update of the European Society of Anaesthesiology and Intensive Care …
Anaesthesiology | EJA Update of the European Society of Anaesthesiology and Intensive Care …
Postoperative delirium is associated with increased plasma neurofilament light
While delirium is associated with cognitive decline and dementia, there is limited evidence
to support causality for this relationship. Clarification of how delirium may cause cognitive …
to support causality for this relationship. Clarification of how delirium may cause cognitive …
Priming microglia for innate immune memory in the brain
Microglia, the resident macrophages of the brain, are highly plastic and well known to be pre-
activated or 'primed'by active inflammatory processes, resulting in amplified responses to a …
activated or 'primed'by active inflammatory processes, resulting in amplified responses to a …