Natural metalloproteins perform many functions—ranging from sensing to electron transfer
and catalysis—in which the position and property of each ligand and metal are dictated by …

Protein design is a valuable tool for understanding the fundamental factors that dictate
protein structure and function. The field of protein design has seen significant progress over …

Proteins are nature's premier building blocks for constructing sophisticated nanoscale
architectures that carry out complex tasks and chemical transformations. Some 70%− 80% of …

Elegant protein assembly to generate new biomaterials undergoes extremely rapid
development for wide extension of biotechnology applications, which can be a powerful tool …

Metal coordination is a key structural and functional component of a large fraction of
proteins. Given this dual role we considered the possibility that metal coordination may have …

The most important experimental quantity describing the thermodynamics of metal-ion
binding with various (in) organic ligands, or biomolecules, is the stability constant of the …

Herein, we evaluate the binding of Pb (II) and Bi (III) to cysteine-substituted versions of the
TRI peptides [AcG-(LKALEEK) 4 G-NH 2] which have previously been shown to bind Hg (II) …

For much of their history, lanthanides were thought to be biologically inert. However, the last
decade has seen the discovery and development of the field of native lanthanide …

The mutual relationship between peptides and metal ions enables metalloproteins to have
crucial roles in biological systems, including structural, sensing, electron transport, and …

The use of de novo designed peptides is a powerful strategy to elucidate HgII–protein
interactions and to gain insight into the chemistry of HgII in biological systems. Cysteine …