Molecular and pharmacological aspects of piperine as a potential molecule for disease prevention and management: evidence from clinical trials

AK Tripathi, AK Ray, SK Mishra - Beni-Suef university journal of basic and …, 2022 - Springer
Background Piperine is a type of amide alkaloid that exhibits pleiotropic properties like
antioxidant, anticancer, anti-inflammatory, antihypertensive, hepatoprotective …

A systematic review on Piper longum L.: Bridging traditional knowledge and pharmacological evidence for future translational research

V Yadav, A Krishnan, D Vohora - Journal of ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance Piper longum, commonly referred as 'Pippali', has found its
traditional use in India, Malaysia, Singapore and other South Asian countries as an …

Gut microbiota dysbiosis contributes to the development of hypertension

J Li, F Zhao, Y Wang, J Chen, J Tao, G Tian, S Wu… - Microbiome, 2017 - Springer
Background Recently, the potential role of gut microbiome in metabolic diseases has been
revealed, especially in cardiovascular diseases. Hypertension is one of the most prevalent …

Piper longum L.: A comprehensive review on traditional uses, phytochemistry, pharmacology, and health‐promoting activities

P Biswas, M Ghorai, T Mishra… - Phytotherapy …, 2022 - Wiley Online Library
Piper longum (family Piperaceae), commonly known as “long‐pepper” or “Pippali” grows as
a perennial shrub or as an herbaceous vine. It is native to the Indo‐Malaya region and …

[HTML][HTML] Overview for various aspects of the health benefits of Piper longum linn. fruit

S Kumar, J Kamboj, S Sharma - Journal of acupuncture and meridian …, 2011 - Elsevier
Herbal remedies have become popular, due in part to the lower risk of adverse reactions.
Thousands of plants have been used traditionally to treat various diseases. Among them …

[PDF][PDF] Chemistry and pharmacology of Piper longum L

M Zaveri, A Khandhar, S Patel… - International journal of …, 2010 - researchgate.net
Earthen hemisphere is gifted with varieties of large number of medicinal herbs. Herbs are
natural remedies for the disease with higher safety profile and efficacy. The country like India …

Piperine, a dietary phytochemical, inhibits angiogenesis

CD Doucette, AL Hilchie, R Liwski… - The Journal of nutritional …, 2013 - Elsevier
Angiogenesis plays an important role in tumor progression. Piperine, a major alkaloid
constituent of black pepper, has diverse physiological actions including killing of cancer …

Piperine inhibits TNF-α induced adhesion of neutrophils to endothelial monolayer through suppression of NF-κB and IκB kinase activation

S Kumar, V Singhal, R Roshan, A Sharma… - European journal of …, 2007 - Elsevier
Piperine displays antipyretic, analgesic, insecticidal and anti-inflammatory activities. It is the
first amide to be isolated from Piper species. In the process of identifying non-steroidal anti …

Gut microbiota and hypertension: From pathogenesis to new therapeutic strategies

Y Kang, Y Cai - Clinics and research in hepatology and …, 2018 - Elsevier
Hypertension (HTN) has become a global public health concern and a major risk factor for
cardiovascular, cerebrovascular, and kidney diseases. The complex interplay of genetic and …

Anti-inflammatory evaluation and characterization of leaf extract of Ananas comosus

S Kargutkar, S Brijesh - Inflammopharmacology, 2018 - Springer
Abstract Ananas comosus (L.) Merr (Pineapple) is a tropical plant with an edible fruit. In the
present study, the potential anti-inflammatory activity of A. comosus leaf extract (ALE) was …