Introduction Urticaria, a mast cell-mediated skin disease, manifests as acute or chronic, with
the latter divided into spontaneous and inducible types and requires individualized …

H1‐antihistamines for chronic spontaneous urticaria - Sharma, M - 2014 | Cochrane Library Skip
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Background Licensed dose second-generation H1-antihistamines (sgAHs) are the first-line
treatment in chronic spontaneous urticaria (CSU). However, the available evidence up to the …

Background The comparative safety and/or dosing regimens of individual second-
generation H1-antihistamines (sgAHs) in patients with chronic urticaria (CU) remain poorly …

Introduction As a substrate of P-glycoprotein, levocetirizine should not cause sedative
effects. However, while cetirizine, a mixture of levocetirizine and dextrocetirizine, can slightly …

Background Chronic spontaneous urticaria is characterized by recurrent itchy wheals. First-
line management is with H1-antihistamines. Objective We sought to conduct a Cochrane …

Background: Chronic urticaria (CU) is a vexing problem and patients of CU suffer from the
morbidity that arise from irritable itch and weals and are also subjected to a huge …

Background: Chronic urticaria is a vexing problem for patients and treating physicians alike.
The EAACI/GA [2] LEN/EDF/WAO guidelines advocate an increased antihistamine dosage …

Background Current guidelines do not recommend performing aeroallergen skin prick
testing (SPT) in chronic spontaneous urticaria (CSU). Objective The objective of this review …

The effects of urticaria are predominantly mediated by histamine release; therefore, H 1-
antihistamines are the mainstay of treatment. Second-generation H 1-antihistamines …