Macronutrient metabolism by the human gut microbiome: major fermentation by-products and their impact on host health

K Oliphant, E Allen-Vercoe - Microbiome, 2019 - Springer
The human gut microbiome is a critical component of digestion, breaking down complex
carbohydrates, proteins, and to a lesser extent fats that reach the lower gastrointestinal tract …

Nutritional components in Western diet versus Mediterranean diet at the gut microbiota–immune system interplay. Implications for health and disease

C García-Montero, O Fraile-Martínez… - Nutrients, 2021 - mdpi.com
The most prevalent diseases of our time, non-communicable diseases (NCDs)(including
obesity, type 2 diabetes, cardiovascular diseases and some types of cancer) are rising …

SER-109, an Oral Microbiome Therapy for Recurrent Clostridioides difficile Infection

P Feuerstadt, TJ Louie, B Lashner… - … England Journal of …, 2022 - Mass Medical Soc
Background Current therapies for recurrent Clostridioides difficile infection do not address
the disrupted microbiome, which supports C. difficile spore germination into toxin-producing …

Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity

W Yang, T Yu, X Huang, AJ Bilotta, L Xu, Y Lu… - Nature …, 2020 - nature.com
Innate lymphoid cells (ILCs) and CD4+ T cells produce IL-22, which is critical for intestinal
immunity. The microbiota is central to IL-22 production in the intestines; however, the factors …

Phytogenic feed additives in poultry: achievements, prospective and challenges

N Abdelli, D Solà-Oriol, JF Pérez - Animals, 2021 - mdpi.com
Simple Summary Plant secondary metabolites and essential oils also known as phytogenics
are biologically active compounds that have recently attracted increased interest as feed …

The role of microbiota in infant health: from early life to adulthood

Y Yao, X Cai, Y Ye, F Wang, F Chen… - Frontiers in …, 2021 - frontiersin.org
From early life to adulthood, the microbiota play a crucial role in the health of the infant. The
microbiota in early life are not only a key regulator of infant health but also associated with …

The intestinal microbiota: antibiotics, colonization resistance, and enteric pathogens

S Kim, A Covington, EG Pamer - Immunological reviews, 2017 - Wiley Online Library
The human gastrointestinal tract hosts a diverse network of microorganisms, collectively
known as the microbiota that plays an important role in health and disease. For instance, the …

Treatment of peanut allergy and colitis in mice via the intestinal release of butyrate from polymeric micelles

R Wang, S Cao, MEH Bashir, LA Hesser, Y Su… - Nature Biomedical …, 2023 - nature.com
The microbiome modulates host immunity and aids the maintenance of tolerance in the gut,
where microbial and food-derived antigens are abundant. Yet modern dietary factors and …

[HTML][HTML] Butyrate-producing Eubacterium rectale suppresses lymphomagenesis by alleviating the TNF-induced TLR4/MyD88/NF-κB axis

H Lu, X Xu, D Fu, Y Gu, R Fan, H Yi, X He, C Wang… - Cell Host & Microbe, 2022 - cell.com
Microbiota-induced tumorigenesis is well established in solid tumors of the gastrointestinal
tract but rarely explored in hematologic malignancies. To determine the role of gut …

Functional and genomic variation between human-derived isolates of Lachnospiraceae reveals inter-and intra-species diversity

MT Sorbara, ER Littmann, E Fontana, TU Moody… - Cell host & …, 2020 - cell.com
Bacteria belonging to the Lachnospiraceae family are abundant, obligate anaerobic
members of the microbiota in healthy humans. Lachnospiraceae impact their hosts by …