Use and abuse of HOMA modeling

TM Wallace, JC Levy, DR Matthews - Diabetes care, 2004 - Am Diabetes Assoc
Homeostatic model assessment (HOMA) is a method for assessing β-cell function and
insulin resistance (IR) from basal (fasting) glucose and insulin or C-peptide concentrations. It …

The human obesity gene map: the 2005 update

T Rankinen, A Zuberi, YC Chagnon, SJ Weisnagel… - …, 2006 - Wiley Online Library
This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …

The genetics of hyperuricaemia and gout

AM Reginato, DB Mount, I Yang, HK Choi - Nature Reviews …, 2012 - nature.com
Gout is a common and very painful inflammatory arthritis caused by hyperuricaemia. This
Review provides an update on the genetics of hyperuricaemia and gout, including findings …

The human obesity gene map: the 2003 update

EE Snyder, B Walts, L Pérusse, YC Chagnon… - Obesity …, 2004 - Wiley Online Library
This is the tenth update of the human obesity gene map, incorporating published results up
to the end of October 2003 and continuing the previous format. Evidence from single‐gene …

The human obesity gene map: the 2004 update

L Pérusse, T Rankinen, A Zuberi, YC Chagnon… - Obesity …, 2005 - Wiley Online Library
This paper presents the eleventh update of the human obesity gene map, which
incorporates published results up to the end of October 2004. Evidence from single‐gene …

The human obesity gene map: the 2002 update

YC Chagnon, T Rankinen, EE Snyder… - Obesity …, 2003 - Wiley Online Library
This is the ninth update of the human obesity gene map, incorporating published results
through October 2002 and continuing the previous format. Evidence from single‐gene …

β3-Adrenoceptors in the cardiovascular system: putative roles in human pathologies

B Rozec, C Gauthier - Pharmacology & therapeutics, 2006 - Elsevier
The sympathetic nervous system is central for the neurohumoral regulation of the
cardiovascular system and is largely involved in many cardiovascular diseases affecting …

The human obesity gene map: the 2001 update

T Rankinen, L Pérusse, SJ Weisnagel… - Obesity …, 2002 - Wiley Online Library
This report constitutes the eighth update of the human obesity gene map, incorporating
published results up to the end of October 2001. Evidence from the rodent and human …

The β3-adrenoceptor as a therapeutic target: current perspectives

MG Ursino, V Vasina, E Raschi, F Crema… - Pharmacological …, 2009 - Elsevier
β3-Adrenoceptors (β3-ARs) are located not only on the plasma membrane of both white and
brown adipocytes, but also exist in human heart, gall bladder, gastrointestinal tract, prostate …

Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia

J Simino, G Shi, JC Bis, DI Chasman, GB Ehret… - The American Journal of …, 2014 - cell.com
Although age-dependent effects on blood pressure (BP) have been reported, they have not
been systematically investigated in large-scale genome-wide association studies (GWASs) …