Long non-coding RNAs (lncRNAs) outnumber protein-coding transcripts, but their functions
remain largely unknown. In this Review, we discuss the emerging roles of lncRNAs in the …

The development of high-throughput RNA structure profiling methods in the past decade has
greatly facilitated our ability to map and characterize different aspects of RNA structures …

Transposable elements (TEs) represent almost half of the human genome. Historically
deemed 'junk DNA', recent technological advancements have stimulated a wave of research …

Alu elements are highly abundant primate-specific short interspersed nuclear elements that
account for~ 10% of the human genome. Due to their preferential location in gene-rich …

Insufficient thyroid hormone production in newborns is referred to as congenital
hypothyroidism. Multinodular goiter (MNG), characterized by an enlarged thyroid gland with …

Alternative transcription start site usage (ATSS) is a widespread regulatory strategy that
enables genes to choose between multiple genomic loci for initiating transcription. This …

Enhancers are noncoding regulatory elements that instruct spatial and temporal specificity of
gene transcription in response to a variety of intrinsic and extrinsic signals during …

It is apparent that various functional units within the cellular machinery are derived from
RNAs. The evolution of sequencing techniques has resulted in significant insights into …

SARS-CoV-2 RNA interacts with host factors to suppress interferon responses and
simultaneously induces cytokine release to drive the development of severe coronavirus …

Long noncoding RNAs (lncRNAs) are a class of RNA molecules exceeding 200 nucleotides
in length that lack long open-reading frames. Transcribed predominantly by RNA …