The AIDS epidemic has been a global public health issue for more than 40 years and has
resulted in~ 40 million deaths. AIDS is caused by the retrovirus, HIV-1, which is transmitted …

Poor medication adherence is a pervasive issue with considerable health and
socioeconomic consequences. Although the underlying reasons are generally understood …

Background There are gaps in uptake of, adherence to, and persistence in the use of
preexposure prophylaxis for human immunodeficiency virus (HIV) prevention among …

Background Oral pre-exposure prophylaxis has been introduced in more than 70 countries,
including many in sub-Saharan Africa, but women experience considerable barriers to daily …

Importance Recent advances in treatment and prevention of HIV warrant updated
recommendations to guide optimal practice. Objective Based on a critical evaluation of new …

The development of antiretroviral therapy for the prevention and treatment of HIV infection
has been marked by a series of remarkable successes. However, the efforts to develop a …

Background Twice-yearly subcutaneous lenacapavir has been shown to be efficacious for
prevention of HIV infection in cisgender women. The efficacy of lenacapavir for preexposure …

Since the first cases of AIDS appeared in 1981, human immunodeficiency virus type 1 (HIV-
1) infection has reached pandemic proportions. Forty years later, research has led to the …

Abstract Background The European AIDS Clinical Society (EACS) guidelines were revised
in 2023 for the 19th time, and all aspects of HIV care were updated. Key Points of the …

Background Poor adherence to oral HIV pre-exposure prophylaxis (PrEP) diminishes its
clinical and public health benefits. This study synthesises evidence regarding …