The Alzheimer's disease assessment scale–cognitive subscale (ADAS-Cog): modifications and responsiveness in pre-dementia populations. a narrative review
JK Kueper, M Speechley… - Journal of Alzheimer's …, 2018 - content.iospress.com
Abstract The Alzheimer's Disease Assessment Scale–Cognitive Subscale (ADAS-Cog) was
developed in the 1980s to assess the level of cognitive dysfunction in Alzheimer's disease …
developed in the 1980s to assess the level of cognitive dysfunction in Alzheimer's disease …
Impact of the Alzheimer's disease neuroimaging initiative, 2004 to 2014
MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2015 - Elsevier
Abstract Introduction The Alzheimer's Disease Neuroimaging Initiative (ADNI) was
established in 2004 to facilitate the development of effective treatments for Alzheimer's …
established in 2004 to facilitate the development of effective treatments for Alzheimer's …
Brain aging patterns in a large and diverse cohort of 49,482 individuals
Brain aging process is influenced by various lifestyle, environmental and genetic factors, as
well as by age-related and often coexisting pathologies. Magnetic resonance imaging and …
well as by age-related and often coexisting pathologies. Magnetic resonance imaging and …
Effects of exercise alone or combined with cognitive training and vitamin D supplementation to improve cognition in adults with mild cognitive impairment: a …
Importance Exercise, cognitive training, and vitamin D may enhance cognition in older
adults with mild cognitive impairment (MCI). Objective To determine whether aerobic …
adults with mild cognitive impairment (MCI). Objective To determine whether aerobic …
Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria
In the past 8 years, both the International Working Group (IWG) and the US National Institute
on Aging–Alzheimer's Association have contributed criteria for the diagnosis of Alzheimer's …
on Aging–Alzheimer's Association have contributed criteria for the diagnosis of Alzheimer's …
High cerebrospinal amyloid-β 42 is associated with normal cognition in individuals with brain amyloidosis
Background Brain amyloidosis does not invariably predict dementia. We hypothesized that
high soluble 42-amino acid β amyloid (Aβ42) peptide levels are associated with normal …
high soluble 42-amino acid β amyloid (Aβ42) peptide levels are associated with normal …
Multiplex cerebrospinal fluid proteomics identifies biomarkers for diagnosis and prediction of Alzheimer's disease
Y Guo, SD Chen, J You, SY Huang, YL Chen… - Nature human …, 2024 - nature.com
Recent expansion of proteomic coverage opens unparalleled avenues to unveil new
biomarkers of Alzheimer's disease (AD). Among 6,361 cerebrospinal fluid (CSF) proteins …
biomarkers of Alzheimer's disease (AD). Among 6,361 cerebrospinal fluid (CSF) proteins …
Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease
Loss of function of TREM2, a key receptor selectively expressed by microglia in the brain,
contributes to the development of Alzheimer's disease (AD). We therefore examined whether …
contributes to the development of Alzheimer's disease (AD). We therefore examined whether …
Cerebrospinal fluid analysis detects cerebral amyloid-β accumulation earlier than positron emission tomography
Abstract See Rabinovici (doi: 10.1093/brain/aww025) for a scientific commentary on this
article. Cerebral accumulation of amyloid-β is thought to be the starting mechanism in …
article. Cerebral accumulation of amyloid-β is thought to be the starting mechanism in …
Earlier Alzheimer's disease onset is associated with tau pathology in brain hub regions and facilitated tau spreading
In Alzheimer's disease (AD), younger symptom onset is associated with accelerated disease
progression and tau spreading, yet the mechanisms underlying faster disease manifestation …
progression and tau spreading, yet the mechanisms underlying faster disease manifestation …