[HTML][HTML] Orientation and characterization of immobilized antibodies for improved immunoassays

NG Welch, JA Scoble, BW Muir, PJ Pigram - Biointerphases, 2017 - pubs.aip.org
Orientation of surface immobilized capture proteins, such as antibodies, plays a critical role
in the performance of immunoassays. The sensitivity of immunodiagnostic procedures is …

Ferritin drug carrier (FDC) for tumor targeting therapy

J He, K Fan, X Yan - Journal of Controlled Release, 2019 - Elsevier
Ferritin is an iron storage protein that plays a key role in iron homeostasis and anti-oxidation
of cells. Due to its unique architecture of 24 self-assembling subunits and hollow cavity …

Antibody‐incorporated nanomedicines for cancer therapy

SY Wu, FG Wu, X Chen - Advanced Materials, 2022 - Wiley Online Library
Antibody‐based cancer therapy, one of the most significant therapeutic strategies, has
achieved considerable success and progress over the past decades. Nevertheless …

Ferritin nanocage: A promising and designable multi-module platform for constructing dynamic nanoassembly-based drug nanocarrier

B Zhang, G Tang, J He, X Yan, K Fan - Advanced Drug Delivery Reviews, 2021 - Elsevier
Ferritin has been widely recognized as an ideal drug delivery vehicle owing to its unique
cage-like structure. Coupled with intrinsic targeting ability and excellent biosafety, ferritin …

Endocytosis and organelle targeting of nanomedicines in cancer therapy

X Wang, Y Qiu, M Wang, C Zhang, T Zhang… - International journal …, 2020 - Taylor & Francis
Nanomedicines (NMs) have played an increasing role in cancer therapy as carriers to
efficiently deliver therapeutics into tumor cells. For this application, the uptake of NMs by …

Transferrin receptor-mediated liposomal drug delivery: Recent trends in targeted therapy of cancer

S Mojarad-Jabali, S Mahdinloo… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Compared to normal cells, malignant cancer cells require more iron for their
growth and rapid proliferation, which can be supplied by a high expression level of …

Amelioration of acute myocardial infarction injury through targeted ferritin nanocages loaded with an ALKBH5 inhibitor

P Cheng, H Han, F Chen, L Cheng, C Ma, H Huang… - Acta biomaterialia, 2022 - Elsevier
The roles of m 6 A RNA methylation and mitochondrial metabolism in acute myocardial
infarction (AMI) remain unclear. In this study, we demonstrated that m 6 A RNA methylation …

Nanotherapeutics for prostate cancer treatment: A comprehensive review

R Hu, J Lan, D Zhang, W Shen - Biomaterials, 2024 - Elsevier
Prostate cancer (PCa) is the most prevalent solid organ malignancy and seriously affects
male health. The adverse effects of prostate cancer therapeutics can cause secondary …

Target delivering paclitaxel by ferritin heavy chain nanocages for glioma treatment

W Liu, Q Lin, Y Fu, S Huang, C Guo, L Li… - Journal of Controlled …, 2020 - Elsevier
Glioma is one of the most common aggressive brain malignancies, but the treatment of
glioma is still far from satisfying. The efficiency of chemotherapy–the major choice of glioma …

Ferritin-based electrochemiluminescence nanosurface energy transfer system for procalcitonin detection using HWRGWVC heptapeptide for site-oriented antibody …

L Yang, D Fan, Y Zhang, C Ding, D Wu… - Analytical …, 2019 - ACS Publications
In this study, an ultrasensitive biosensor based on a novel electrochemiluminescence
nanosurface energy transfer (ECL-NSET) system was developed for procalcitonin (PCT) …