Gap genes are involved in segment determination during the early development of the fruit
fly Drosophila melanogaster as well as in other insects. This review attempts to synthesize …

The TRANSFAC® database on transcription factors, their binding sites, nucleotide
distribution matrices and regulated genes as well as the complementing database …

Comparative analysis of multiple genomes in a phylogenetic framework dramatically
improves the precision and sensitivity of evolutionary inference, producing more robust …

Divergent morphology of species has largely been ascribed to genetic differences in the
tissue-specific expression of proteins, which could be achieved by divergence in cis …

The sequencing and annotation of the Drosophila melanogaster genome, first published in
2000 through collaboration between Celera Genomics and the Drosophila Genome …

ABSTRACT JASPAR (http://jaspar. genereg. net) is the leading open-access database of
matrix profiles describing the DNA-binding patterns of transcription factors (TFs) and other …

We describe the comprehensive characterization of homeodomain DNA-binding specificities
from a metazoan genome. The analysis of all 84 independent homeodomains from D …

Abstract The Open Regulatory Annotation database (ORegAnno) is a resource for curated
regulatory annotation. It contains information about regulatory regions, transcription factor …

STAMP is a newly developed web server that is designed to support the study of DNA-
binding motifs. STAMP may be used to query motifs against databases of known motifs; the …

Since its beginning as a data collection more than 20 years ago, the TRANSFAC project
underwent an evolution to become the basis for a complex platform for the description and …