Synaptic memory and CaMKII

RA Nicoll, H Schulman - Physiological reviews, 2023 - journals.physiology.org
Ca2+/calmodulin-dependent protein kinase II (CaMKII) and long-term potentiation (LTP)
were discovered within a decade of each other and have been inextricably intertwined ever …

The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB

ER Kandel - Molecular brain, 2012 - Springer
The analysis of the contributions to synaptic plasticity and memory of cAMP, PKA, CRE,
CREB-1, CREB-2, and CPEB has recruited the efforts of many laboratories all over the …

Reactive oxygen species: Physiological and physiopathological effects on synaptic plasticity: Supplementary issue: Brain plasticity and repair

TF Beckhauser, J Francis-Oliveira… - Journal of …, 2016 - journals.sagepub.com
In the mammalian central nervous system, reactive oxygen species (ROS) generation is
counterbalanced by antioxidant defenses. When large amounts of ROS accumulate …

A synaptic model of memory: long-term potentiation in the hippocampus

TVP Bliss, GL Collingridge - Nature, 1993 - nature.com
Long-term potentiation of synaptic transmission in the hippocampus is the primary
experimental model for investigating the synaptic basis of learning and memory in …

[LIVRE][B] Spiking neuron models: Single neurons, populations, plasticity

W Gerstner, WM Kistler - 2002 - books.google.com
Neurons in the brain communicate by short electrical pulses, the so-called action potentials
or spikes. How can we understand the process of spike generation? How can we …

Synapses and memory storage

M Mayford, SA Siegelbaum… - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
The synapse is the functional unit of the brain. During the last several decades we have
acquired a great deal of information on its structure, molecular components, and …

LTP and LTD: an embarrassment of riches

RC Malenka, MF Bear - Neuron, 2004 - cell.com
LTP and LTD, the long-term potentiation and depression of excitatory synaptic transmission,
are widespread phenomena expressed at possibly every excitatory synapse in the …

[HTML][HTML] Long-term potentiation and memory

MA Lynch - Physiological reviews, 2004 - journals.physiology.org
Abstract Lynch, MA. Long-Term Potentiation and Memory. Physiol Rev 84: 87–136, 2004;
10.1152/physrev. 00014.2003.—One of the most significant challenges in neuroscience is to …

Long-term potentiation--a decade of progress?

RC Malenka, RA Nicoll - Science, 1999 - science.org
Long-term potentiation of synaptic transmission in the hippocampus is the leading
experimental model for the synaptic changes that may underlie learning and memory. This …

The heme oxygenase system: a regulator of second messenger gases

MD Maines - Annual review of pharmacology and toxicology, 1997 - annualreviews.org
▪ Abstract The heme oxygenase (HO) system consists of two forms identified to date: the
oxidative stress–inducible protein HO-1 (HSP32) and the constitutive isozyme HO-2. These …