Nanoparticle-based delivery systems for vaccines
Vaccination is still the most cost-effective way to combat infectious illnesses. Conventional
vaccinations may have low immunogenicity and, in most situations, only provide partial …
vaccinations may have low immunogenicity and, in most situations, only provide partial …
The biology and treatment of Merkel cell carcinoma: current understanding and research priorities
PW Harms, KL Harms, PS Moore… - Nature reviews Clinical …, 2018 - nature.com
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer associated with
advanced age and immunosuppression. Over the past decade, an association has been …
advanced age and immunosuppression. Over the past decade, an association has been …
Why do viruses cause cancer? Highlights of the first century of human tumour virology
The year 2011 marks the centenary of Francis Peyton Rous's landmark experiments on an
avian cancer virus. Since then, seven human viruses have been found to cause 10–15% of …
avian cancer virus. Since then, seven human viruses have been found to cause 10–15% of …
Virosome-based nanovaccines; a promising bioinspiration and biomimetic approach for preventing viral diseases: A review
Vaccination is the most effective means of controlling infectious disease-related morbidity
and mortality. However, due to low immunogenicity of viral antigens, nanomedicine as a …
and mortality. However, due to low immunogenicity of viral antigens, nanomedicine as a …
Virus-like particles as preventive and therapeutic cancer vaccines
Virus-like particles (VLPs) are self-assembled viral protein complexes that mimic the native
virus structure without being infectious. VLPs, similarly to wild type viruses, are able to …
virus structure without being infectious. VLPs, similarly to wild type viruses, are able to …
Viral oncoprotein antibodies as a marker for recurrence of Merkel cell carcinoma: a prospective validation study
BACKGROUND Merkel cell carcinoma (MCC) is an aggressive skin cancer with a
recurrence rate of> 40%. Of the 2000 MCC cases per year in the United States, most are …
recurrence rate of> 40%. Of the 2000 MCC cases per year in the United States, most are …
[HTML][HTML] Merkel cell polyomavirus: a newly discovered human virus with oncogenic potential
ME Spurgeon, PF Lambert - Virology, 2013 - Elsevier
A marked escalation in the rate of discovery of new types of human polyomavirus has
occurred over the last five years largely owing to recent technological advances in their …
occurred over the last five years largely owing to recent technological advances in their …
Biology, evolution, and medical importance of polyomaviruses: An update
U Moens, A Krumbholz, B Ehlers, R Zell… - Infection, Genetics and …, 2017 - Elsevier
The family Polyomaviridae encompasses non-enveloped viruses with a circular dsDNA
genome that is typically approximately 5000 bp in length. Originally isolated from mammals …
genome that is typically approximately 5000 bp in length. Originally isolated from mammals …
Antibodies to merkel cell polyomavirus T antigen oncoproteins reflect tumor burden in merkel cell carcinoma patients
Merkel cell polyomavirus (MCPyV) is a common infectious agent that is likely involved in the
etiology of most Merkel cell carcinomas (MCC). Serum antibodies recognizing the MCPyV …
etiology of most Merkel cell carcinomas (MCC). Serum antibodies recognizing the MCPyV …
Identification of a novel human polyomavirus in organs of the gastrointestinal tract
S Korup, J Rietscher, S Calvignac-Spencer, F Trusch… - PloS one, 2013 - journals.plos.org
Polyomaviruses are small, non-enveloped viruses with a circular double-stranded DNA
genome. Using a generic polyomavirus PCR targeting the VP1 major structural protein …
genome. Using a generic polyomavirus PCR targeting the VP1 major structural protein …