Matrix metalloproteinases in cancer: their value as diagnostic and prognostic markers and therapeutic targets

E Hadler-Olsen, JO Winberg, L Uhlin-Hansen - Tumor Biology, 2013 - Springer
Biomarkers are used as tools in cancer diagnostics and in treatment stratification. In most
cancers, there are increased levels of one or several members of the matrix …

Graphene-based field effect transistor biosensors for breast cancer detection: A review on biosensing strategies

I Novodchuk, M Bajcsy, M Yavuz - Carbon, 2021 - Elsevier
Breast cancer (BC) is the most occurring cancer in females and the second most commonly
occurring cancer world-wide. Early detection of BC may ease the treatment and prevent the …

Mangiferin exerts antitumor activity in breast cancer cells by regulating matrix metalloproteinases, epithelial to mesenchymal transition, and β-catenin signaling …

H Li, J Huang, B Yang, T **ang, X Yin, W Peng… - Toxicology and applied …, 2013 - Elsevier
Although mangiferin which is a naturally occurring glucosylxanthone has exhibited
promising anticancer activities, the detailed molecular mechanism of mangiferin on cancers …

Matrix metalloproteinase responsive, proximity‐activated polymeric nanoparticles for siRNA delivery

H Li, SS Yu, M Miteva, CE Nelson… - Advanced functional …, 2013 - Wiley Online Library
Small interfering RNA (siRNA) has significant potential to evolve into a new class of
pharmaceutical inhibitors, but technologies that enable robust, tissue‐specific intracellular …

Novel genetic markers of breast cancer survival identified by a genome-wide association study

XO Shu, J Long, W Lu, C Li, WY Chen, R Delahanty… - Cancer research, 2012 - AACR
Only two genome-wide association studies (GWAS) have been conducted to date to identify
potential markers for total mortality after diagnosis of breast cancer. Here, we report the …

Landscape analysis of matrix metalloproteinases unveils key prognostic markers for patients with breast cancer

T Cheng, P Chen, J Chen, Y Deng, C Huang - Frontiers in Genetics, 2022 - frontiersin.org
Breast cancer (BRCA) is the most common cancer in the world, of which incidence rate and
mortality are the highest in women. Being responsible for the remodeling and degradation of …

Prognostic significance of matrix metalloproteinase-7 in gastric cancer survival: a meta-analysis

S Soleyman-Jahi, S Nedjat, A Abdirad, N Hoorshad… - PloS one, 2015 - journals.plos.org
The prognostic role of matrix metalloproteinase-7 in gastric cancer survival has been widely
evaluated. However, the results are controversial. We aimed to set up a meta-analysis to …

Common germline polymorphisms associated with breast cancer-specific survival

A Pirie, Q Guo, P Kraft, S Canisius, DM Eccles… - Breast cancer …, 2015 - Springer
Introduction Previous studies have identified common germline variants nominally
associated with breast cancer survival. These associations have not been widely replicated …

Current evidence on the relationship between four polymorphisms in the matrix metalloproteinases (MMP) gene and breast cancer risk: a meta-analysis

P Zhou, LF Du, GQ Lv, XM Yu, YL Gu, JP Li… - Breast cancer research …, 2011 - Springer
The matrix metalloproteinases (MMP) can degrade various components of the extracellular
matrix and its functional genetic polymorphisms may be associated with breast cancer risk …

SMSPL: robust multimodal approach to integrative analysis of multiomics data

Z Yang, N Wu, Y Liang, H Zhang… - IEEE Transactions on …, 2020 - ieeexplore.ieee.org
With the recent advancement of technologies, it is progressively easier to collect diverse
types of genome-wide data. It is commonly expected that by analyzing these data in an …