[HTML][HTML] Hypoxia in aging and aging-related diseases: mechanism and therapeutic strategies

Y Wei, S Giunta, S **a - International journal of molecular sciences, 2022 - mdpi.com
As the global aging process continues to lengthen, aging-related diseases (eg, chronic
obstructive pulmonary disease (COPD), heart failure) continue to plague the elderly …

A narrative review of periodic breathing during sleep at high altitude: From acclimatizing lowlanders to adapted highlanders

A Patrician, JD Anholm, PN Ainslie - The Journal of Physiology, 2024 - Wiley Online Library
Periodic breathing during sleep at high altitude is almost universal among sojourners. Here,
in the context of acclimatization and adaptation, we provide a contemporary review on …

Excessive erythrocytosis and chronic mountain sickness in dwellers of the highest city in the world

I Hancco, S Bailly, S Baillieul, S Doutreleau… - Frontiers in …, 2020 - frontiersin.org
Background While millions of people are living permanently at high altitude (> 2,500 m)
worldwide, the mechanisms underlying their tolerance to chronic hypoxia and those …

[Књига][B] Ward, Milledge and West's high altitude medicine and physiology

AM Luks, PN Ainslie, JS Lawley, RC Roach… - 2021 - taylorfrancis.com
This pre-eminent work has developed over six editions in response to man's attempts to
climb higher and higher unaided, and to spend more time at altitude for both work and …

Cardiac function and pulmonary hypertension in Central Asian highlanders at 3250 m

M Lichtblau, S Saxer, M Furian… - European …, 2020 - publications.ersnet.org
The question addressed by the study Chronic exposure to hypoxia increases pulmonary
artery pressure (PAP) in highlanders, but the criteria for diagnosis of high-altitude pulmonary …

Long-term chronic intermittent hypoxia: a particular form of chronic high-altitude pulmonary hypertension

J Brito, P Siques, E Pena - Pulmonary Circulation, 2020 - journals.sagepub.com
In some subjects, high-altitude hypobaric hypoxia leads to high-altitude pulmonary
hypertension. The threshold for the diagnosis of high-altitude pulmonary hypertension is a …

Long-term intermittent work at high altitude: right heart functional and morphological status and associated cardiometabolic factors

J Brito, P Siques, R López, R Romero… - frontiers in …, 2018 - frontiersin.org
Background: Living at high altitude or with chronic hypoxia implies functional and
morphological changes in the right ventricle and pulmonary vasculature with a 10 …

Hypoxia and aging: molecular mechanisms, diseases, and therapeutic targets

A Nisar, S Khan, W Li, L Hu, PN Samarawickrama… - MedComm, 2024 - Wiley Online Library
Aging is a complex biological process characterized by the gradual decline of cellular
functions, increased susceptibility to diseases, and impaired stress responses. Hypoxia …

[HTML][HTML] Sleep apnea in school-age children living at high altitude

M Grimm, A Seglias, L Ziegler, M Mademilov, E Isaeva… - Pulmonology, 2023 - Elsevier
Introduction Among adults, sleep apnea is more common in highlanders than in lowlanders.
We evaluated the sleep apnea prevalence in children living at high altitude compared to age …

Chinese medicinal plants for the potential management of high-altitude pulmonary oedema and pulmonary hypertension

T Wang, J Hou, W **ao, Y Zhang, L Zhou… - Pharmaceutical …, 2020 - Taylor & Francis
Context Despite the abundance of knowledge regarding high-altitude pulmonary edoema
(HAPE) and high-altitude pulmonary hypertension (HAPH), their prevalence continues to be …