Review and comparative assessment of sequence-based predictors of protein-binding residues

J Zhang, L Kurgan - Briefings in bioinformatics, 2018 - academic.oup.com
Understanding of molecular mechanisms that govern protein–protein interactions and
accurate modeling of protein–protein docking rely on accurate identification and prediction …

Protein–protein interaction predictions using text mining methods

N Papanikolaou, GA Pavlopoulos, T Theodosiou… - Methods, 2015 - Elsevier
It is beyond any doubt that proteins and their interactions play an essential role in most
complex biological processes. The understanding of their function individually, but also in …

iPPI-Esml: an ensemble classifier for identifying the interactions of proteins by incorporating their physicochemical properties and wavelet transforms into PseAAC

J Jia, Z Liu, X **ao, B Liu, KC Chou - Journal of theoretical biology, 2015 - Elsevier
A cell contains thousands of proteins. Many important functions of cell are carried out
through the proteins therein. Proteins rarely function alone. Most of their functions essential …

Prediction of protein-protein interactions from amino acid sequences with ensemble extreme learning machines and principal component analysis

ZH You, YK Lei, L Zhu, J **a, B Wang - BMC bioinformatics, 2013 - Springer
Abstract Background Protein-protein interactions (PPIs) play crucial roles in the execution of
various cellular processes and form the basis of biological mechanisms. Although large …

[HTML][HTML] Deep neural network based predictions of protein interactions using primary sequences

H Li, XJ Gong, H Yu, C Zhou - Molecules, 2018 - mdpi.com
Machine learning based predictions of protein–protein interactions (PPIs) could provide
valuable insights into protein functions, disease occurrence, and therapy design on a large …

[HTML][HTML] iStable 2.0: Predicting protein thermal stability changes by integrating various characteristic modules

CW Chen, MH Lin, CC Liao, HP Chang… - Computational and …, 2020 - Elsevier
Protein mutations can lead to structural changes that affect protein function and result in
disease occurrence. In protein engineering, drug design or and optimization industries …

Machine learning models for prediction of co-occurrence of diabetes and cardiovascular diseases: a retrospective cohort study

AS Abdalrada, J Abawajy, T Al-Quraishi… - Journal of Diabetes & …, 2022 - Springer
Background Diabetic mellitus (DM) and cardiovascular diseases (CVD) cause significant
healthcare burden globally and often co-exists. Current approaches often fail to identify …

Predicting protein-protein interactions from primary protein sequences using a novel multi-scale local feature representation scheme and the random forest

ZH You, KCC Chan, P Hu - PloS one, 2015 - journals.plos.org
The study of protein-protein interactions (PPIs) can be very important for the understanding
of biological cellular functions. However, detecting PPIs in the laboratories are both time …

StackDPPred: a stacking based prediction of DNA-binding protein from sequence

A Mishra, P Pokhrel, MT Hoque - Bioinformatics, 2019 - academic.oup.com
Motivation Identification of DNA-binding proteins from only sequence information is one of
the most challenging problems in the field of genome annotation. DNA-binding proteins play …

Prediction of protein-protein interactions from amino acid sequences using a novel multi-scale continuous and discontinuous feature set

ZH You, L Zhu, CH Zheng, HJ Yu, SP Deng, Z Ji - BMC bioinformatics, 2014 - Springer
Background Identifying protein-protein interactions (PPIs) is essential for elucidating protein
functions and understanding the molecular mechanisms inside the cell. However, the …