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Diagnostic biomarkers in ovarian cancer: advances beyond CA125 and HE4
Ovarian cancer (OC) is the most lethal gynaecologic malignancy, attributed to its insidious
growth, non-specific symptoms and late presentation. Unfortunately, current screening …
growth, non-specific symptoms and late presentation. Unfortunately, current screening …
Proteomic applications for the early detection of cancer
The ability of physicians to effectively treat and cure cancer is directly dependent on their
ability to detect cancers at their earliest stages. Proteomic analyses of early-stage cancers …
ability to detect cancers at their earliest stages. Proteomic analyses of early-stage cancers …
Cancer-associated mesothelial cells promote ovarian cancer chemoresistance through paracrine osteopontin signaling
Ovarian cancer is the leading cause of gynecological malignancy–related deaths, due to its
widespread intraperitoneal metastases and acquired chemoresistance. Mesothelial cells are …
widespread intraperitoneal metastases and acquired chemoresistance. Mesothelial cells are …
[HTML][HTML] The response and resistance to drugs in ovarian cancer cell lines in 2D monolayers and 3D spheroids
Ovarian cancer is the most common type of gynecologic cancer. One of the leading causes
of high mortality is chemoresistance, developed primarily or during treatment. Different …
of high mortality is chemoresistance, developed primarily or during treatment. Different …
The use of multiple novel tumor biomarkers for the detection of ovarian carcinoma in patients with a pelvic mass
OBJECTIVES.: The CA125 tumor marker is used to help predict the presence of ovarian
cancer in patients with an adnexal mass. Because elevated CA125 levels occur in many …
cancer in patients with an adnexal mass. Because elevated CA125 levels occur in many …
National Academy of Clinical Biochemistry laboratory medicine practice guidelines for use of tumor markers in testicular, prostate, colorectal, breast, and ovarian …
Abstract Background: Updated National Academy of Clinical Biochemistry (NACB)
Laboratory Medicine Practice Guidelines for the use of tumor markers in the clinic have been …
Laboratory Medicine Practice Guidelines for the use of tumor markers in the clinic have been …
Osteopontin: a key regulator of tumor progression and immunomodulation
Simple Summary Anti-PD-1/PD-L1 and anti-CTLA-4-based immune checkpoint blockade
(ICB) immunotherapy have recently emerged as a breakthrough in human cancer treatment …
(ICB) immunotherapy have recently emerged as a breakthrough in human cancer treatment …
Molecular circuits shared by placental and cancer cells, and their implications in the proliferative, invasive and migratory capacities of trophoblasts
C Ferretti, L Bruni, V Dangles-Marie… - Human reproduction …, 2007 - academic.oup.com
Trophoblast research over the past decades has underlined the striking similarities between
the proliferative, migratory and invasive properties of placental cells and those of cancer …
the proliferative, migratory and invasive properties of placental cells and those of cancer …
[HTML][HTML] Progress and challenges in screening for early detection of ovarian cancer
Ovarian cancer is characterize by few early symptoms, presentation at an advanced stage,
and poor survival. As a result, it is the most frequent cause of death from gynecological …
and poor survival. As a result, it is the most frequent cause of death from gynecological …
Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum
Genetic alterations in tumor cells often lead to the emergence of growth-stimulatory
autocrine and paracrine signals, involving overexpression of secreted peptide growth …
autocrine and paracrine signals, involving overexpression of secreted peptide growth …