Vaccine derived poliovirus (VDPV)

A Mohanty, R Rohilla, K Zaman, V Hada… - Le Infezioni in …, 2023 - pmc.ncbi.nlm.nih.gov
Poliomyelitis is caused by Poliovirus, a member of a large group of enteroviruses. Vaccine-
derived polioviruses (VDPVs) stem from mutated live poliovirus, which is contained in the …

Genetic stabilization of attenuated oral vaccines against poliovirus types 1 and 3

MT Yeh, M Smith, S Carlyle, JL Konopka-Anstadt… - Nature, 2023 - nature.com
Vaccination with Sabin, a live attenuated oral polio vaccine (OPV), results in robust intestinal
and humoral immunity and has been key to controlling poliomyelitis. As with any RNA virus …

Asymptomatic immunodeficiency-associated vaccine-derived poliovirus infections in two UK children

A Singanayagam, D Klapsa, S Burton-Fanning… - Nature …, 2023 - nature.com
Increasing detections of vaccine-derived poliovirus (VDPV) globally, including in countries
previously declared polio free, is a public health emergency of international concern …

The growing threat of wild poliovirus 1 and vaccine-derived cases in the COVID-19 era

C Franco-Paredes, AJ Rodriguez-Morales… - The Lancet Infectious …, 2022 - thelancet.com
Comment www. thelancet. com/infection Vol 22 October 2022 1413 decreased surveillance
of acute flaccid paralysis are not addressed with alacrity. 1–3 Detection of vaccine-derived …

[HTML][HTML] Wide circulation of type 1 vaccine-derived poliovirus strains in clinical specimens from suspected cases of poliomyelitis, their contacts and in wastewater in …

J Raharinantoanina, ML Joffret, M Bessaud… - Virology, 2024 - Elsevier
Madagascar has faced three major outbreaks of vaccine-derived polioviruses (VDPVs) in
recent decades, with VDPV type 1 reemerging in late 2020. Here, we report the molecular …

Progresses Toward Polio Eradication in Asian Countries: Its History and Japan's Contributions

M Toizumi, M Takamatsu, K Toda… - The Pediatric Infectious …, 2024 - journals.lww.com
Japan experienced a large outbreak of wild poliovirus in the 1960s. The government made
an exceptional decision to import oral polio vaccines (OPVs) from the Soviet Union and …

Vaccine refusal: a major, underestimated obstacle for the Poliomyelitis Eradication Initiative

B Seytre - The American Journal of Tropical Medicine and …, 2023 - pmc.ncbi.nlm.nih.gov
In 1988, the WHO launched the Global Poliomyelitis Eradication Initiative with the goal of
eradication by 2000. Not only has this goal, which has been repeatedly postponed, still not …

Prevalence of vaccine-derived poliovirus in sewage waters in Maiduguri, Borno State, Nigeria

SB Bislava, A Daja, BS Oderinde… - Le Infezioni in …, 2024 - pmc.ncbi.nlm.nih.gov
After a long global battle with wild poliovirus, the virus has been defeated through
researches and vaccination using the oral polio vaccine and inactivated polio vaccine as …

Build back the confidence”: qualitative exploration of community experiences with polio vaccination in the Covid-19 context in Cameroon and Ethiopia

L Lorenzetti, CMP Alam, E Namey, C Monj… - BMC Public Health, 2024 - Springer
Abstract Background In 2020, as the Global Polio Eradication Initiative worked to address
outbreaks of vaccine-derived poliovirus Type 2, particularly in sub-Saharan Africa, the Covid …

[PDF][PDF] Public Health Surveillance of Pediatric Polio in Pakistan: A Cohort Study

LS Rajput, S Noor, MM Khan, M Sajjad, S Farooq… - Cureus, 2024 - cureus.com
Results The highest incidence of polio was observed in children aged 13-24 months (nine
patients, 34.62%), with males accounting for 14 cases (53.85%) and urban residents 16 …