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NETworking with cancer: The bidirectional interplay between cancer and neutrophil extracellular traps
Neutrophils are major effectors and regulators of the immune system. They play critical roles
not only in the eradication of pathogens but also in cancer initiation and progression …
not only in the eradication of pathogens but also in cancer initiation and progression …
Neutrophil phenotypes and functions in cancer: A consensus statement
Neutrophils are the first responders to infection and inflammation and are thus a critical
component of innate immune defense. Understanding the behavior of neutrophils as they …
component of innate immune defense. Understanding the behavior of neutrophils as they …
Neutrophils in cancer carcinogenesis and metastasis
S **ong, L Dong, L Cheng - Journal of hematology & oncology, 2021 - Springer
In recent years, neutrophils have attracted increasing attention because of their cancer-
promoting effects. An elevated neutrophil-to-lymphocyte ratio is considered a prognostic …
promoting effects. An elevated neutrophil-to-lymphocyte ratio is considered a prognostic …
Neutrophils in cancer: heterogeneous and multifaceted
Neutrophils are the most abundant myeloid cells in human blood and are emerging as
important regulators of cancer. However, their functional importance has often been …
important regulators of cancer. However, their functional importance has often been …
Neutrophils in Cancer immunotherapy: friends or foes?
X Huang, E Nepovimova, V Adam, L Sivak, Z Heger… - Molecular cancer, 2024 - Springer
Neutrophils play a Janus-faced role in the complex landscape of cancer pathogenesis and
immunotherapy. As immune defense cells, neutrophils release toxic substances, including …
immunotherapy. As immune defense cells, neutrophils release toxic substances, including …
Dual effect of immune cells within tumour microenvironment: pro-and anti-tumour effects and their triggers
AC Peña-Romero, E Orenes-Piñero - Cancers, 2022 - mdpi.com
Simple Summary The relationship between the immune system and tumours is currently one
of the most studied topics in the field of cancer. Previously, it was thought that a tumour could …
of the most studied topics in the field of cancer. Previously, it was thought that a tumour could …
Tumor associated neutrophils. Their role in tumorigenesis, metastasis, prognosis and therapy
MT Masucci, M Minopoli, MV Carriero - Frontiers in oncology, 2019 - frontiersin.org
Tumor Associated Neutrophils (TANs) are engaged into the tumor microenvironment by
cytokines and chemokines, can be distinguished according to their activation and cytokine …
cytokines and chemokines, can be distinguished according to their activation and cytokine …
Neutrophils in physiology and pathology
A Aroca-Crevillén, T Vicanolo, S Ovadia… - Annual Review of …, 2024 - annualreviews.org
Infections, cardiovascular disease, and cancer are major causes of disease and death
worldwide. Neutrophils are inescapably associated with each of these health concerns, by …
worldwide. Neutrophils are inescapably associated with each of these health concerns, by …
Engineering and targeting neutrophils for cancer therapy
J Zhang, J Gu, X Wang, C Ji, D Yu, M Wang… - Advanced …, 2024 - Wiley Online Library
Neutrophils are the most abundant white blood cells in the circulation and act as the first line
of defense against infections. Increasing evidence suggests that neutrophils possess …
of defense against infections. Increasing evidence suggests that neutrophils possess …
Neutrophils in cancer: neutral no more
Neutrophils are indispensable antagonists of microbial infection and facilitators of wound
healing. In the cancer setting, a newfound appreciation for neutrophils has come into view …
healing. In the cancer setting, a newfound appreciation for neutrophils has come into view …