An organism's survival can depend on its ability to recall and navigate to spatial locations
associated with rewards, such as food or a home. Accumulating research has revealed that …

It has long been hypothesized that conditioning mechanisms play major roles in addiction.
Specifically, the associations between rewarding properties of drugs of abuse and the drug …

Conditioned place preference (CPP) continues to be one of the most popular models to
study the motivational effects of drugs and non‐drug treatments in experimental animals …

The discovery that the adult mammalian brain creates new neurons from pools of stemlike
cells was a breakthrough in neuroscience. Interestingly, this particular new form of structural …

The present study tested the hypothesis that separate neural substrates mediate cocaine
relapse elicited by drug-associated contextual stimuli vs explicit conditioned stimuli (CSs) …

The hippocampus is a heterogeneous structure, comprising histologically distinguishable
subfields. These subfields are differentially involved in memory consolidation, spatial …

The capacity to remember our past experiences and organize our future draws on a number
of cognitive processes that allow our brain to form and store neural representations that can …

The hippocampus provides the brain's memory system with a subset of neurons holding a
map-like representation of each environment experienced. We found in mice that …

Conditioned place preference (CPP) is a widely used model of addiction-related behavior
whose underlying mechanisms are not understood. In this study, we used dual site silicon …

In human addicts, craving and relapse are frequently evoked by the recall of memories
connected to a drug experience. Established memories can become labile if recalled and …