Abstract This Review Article is focused on the action of the reactive oxygenated species in
inducing oxidative injury of the lipid membrane components, as well as on the ability of …

Free radical production occurs continuously in all cells as part of normal cellular function.
However, excess free radical production originating from endogenous or exogenous …

A common metabolic alteration in the tumor microenvironment (TME) is lipid accumulation, a
feature associated with immune dysfunction. Here, we examined how CD8+ tumor infiltrating …

Dyslipidaemia has a prominent role in the onset of notorious atherosclerosis, a disease of
medium to large arteries. Atherosclerosis is the prime root of cardiovascular events …

Diabetes mellitus is a chronic condition that occurs when the body cannot produce enough
or effectively use of insulin. Compared with individuals without diabetes, patients with type 2 …

Oxidative stress, defined as a disturbance in the balance between the production of reactive
oxygen species (free radicals) and antioxidant defenses, is discussed in relation to its …

The clinical events resulting from atherosclerosis are directly related to the oxidation of lipids
in LDLs that become trapped in the extracellular matrix of the subendothelial space. These …

A constant supply of oxygen is indispensable for cardiac viability and function. However, the
role of oxygen and oxygen-associated processes in the heart is complex, and they and can …

M any processes have been implicated in early atherogenesis. These include endothelial
denudation, injury, or activation, including shear stress-related events; local adherence of …

Examines the relationship between the increase in plasma cholesterol and the risk of clinical
coronary artery disease (CAD). Importance of the oxidative modification of low-density …