Ion mobility mass spectrometry in the omics era: Challenges and opportunities for metabolomics and lipidomics

G Paglia, AJ Smith, G Astarita - Mass spectrometry reviews, 2022 - Wiley Online Library
Researchers worldwide are taking advantage of novel, commercially available,
technologies, such as ion mobility mass spectrometry (IM‐MS), for metabolomics and …

Ion mobility mass spectrometry for large Synthetic molecules: Expanding the analytical toolbox

N Geue, REP Winpenny, PE Barran - Journal of the American …, 2024 - ACS Publications
Understanding the composition, structure and stability of larger synthetic molecules is crucial
for their design, yet currently the analytical tools commonly used do not always provide this …

SLIM ultrahigh resolution ion mobility spectrometry separations of isotopologues and isotopomers reveal mobility shifts due to mass distribution changes

R Wojcik, G Nagy, IK Attah, IK Webb… - Analytical …, 2019 - ACS Publications
We report on separations of ion isotopologues and isotopomers using ultrahigh-resolution
traveling wave-based Structures for Lossless Ion Manipulations with serpentine ultralong …

Integrating the potential of ion mobility spectrometry-mass spectrometry in the separation and structural characterisation of lipid isomers

SM Camunas-Alberca, M Moran-Garrido… - Frontiers in Molecular …, 2023 - frontiersin.org
It is increasingly evident that a more detailed molecular structure analysis of isomeric lipids
is critical to better understand their roles in biological processes. The occurrence of isomeric …

[HTML][HTML] Insights of ion mobility spectrometry and its application on food safety and authenticity: A review

E Te Brinke, A Arrizabalaga-Larrañaga… - Analytica chimica …, 2022 - Elsevier
Ion mobility spectrometry (IMS) is gaining importance in the field of food safety and
authenticity in recent years due to its main potential to overcome the challenges that arise …

Collision cross-section calibration strategy for lipid measurements in SLIM-based high-resolution ion mobility

BS Rose, JC May, AR Reardon… - Journal of the American …, 2022 - ACS Publications
Structures for lossless ion manipulation-based high-resolution ion mobility (HRIM) interfaced
with mass spectrometry has emerged as a powerful tool for the separation and analysis of …

General method to obtain collision cross-section values in multipass high-resolution cyclic ion mobility separations

SC Habibi, G Nagy - Analytical chemistry, 2023 - ACS Publications
In recent years, ion mobility spectrometry-mass spectrometry (IMS-MS) has advanced the
field of omics-based research, especially with the development of high-resolution platforms; …

Unraveling the isomeric heterogeneity of glycans: ion mobility separations in structures for lossless ion manipulations

VB Sandilya - Chemical Communications, 2018 - pubs.rsc.org
To address the challenges associated with glycan analyses, we have implemented a
structures for lossless ion manipulations (SLIM) serpentine ultra-long path with extended …

Structural studies of supramolecular complexes and assemblies by ion mobility mass spectrometry

MM Zimnicka - Mass Spectrometry Reviews, 2024 - Wiley Online Library
Recent advances in instrumentation and development of computational strategies for ion
mobility mass spectrometry (IM‐MS) studies have contributed to an extensive growth in the …

The emerging role of ion mobility-mass spectrometry in lipidomics to facilitate lipid separation and identification

J Tu, Z Zhou, T Li, ZJ Zhu - TrAC Trends in Analytical Chemistry, 2019 - Elsevier
Lipids represent an important class of biomolecules, and play numerous roles in
physiological and pathological processes and activates. The enormous chemical and …