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Fiber-type shifting in sarcopenia of old age: proteomic profiling of the contractile apparatus of skeletal muscles
The progressive loss of skeletal muscle mass and concomitant reduction in contractile
strength plays a central role in frailty syndrome. Age-related neuronal impairments are …
strength plays a central role in frailty syndrome. Age-related neuronal impairments are …
The effects of acute and chronic exercise on skeletal muscle proteome
Skeletal muscle plasticity and its adaptation to exercise is a topic that is widely discussed
and investigated due to its primary role in the field of exercise performance and health …
and investigated due to its primary role in the field of exercise performance and health …
The endogenous molecular clock orchestrates the temporal separation of substrate metabolism in skeletal muscle
Background Skeletal muscle is a major contributor to whole-body metabolism as it serves as
a depot for both glucose and amino acids, and is a highly metabolically active tissue. Within …
a depot for both glucose and amino acids, and is a highly metabolically active tissue. Within …
Influence of vitamin C and vitamin E on redox signaling: Implications for exercise adaptations
The exogenous antioxidants vitamin C (ascorbate) and vitamin E (α-tocopherol) often blunt
favorable cell signaling responses to exercise, suggesting that redox signaling contributes to …
favorable cell signaling responses to exercise, suggesting that redox signaling contributes to …
[HTML][HTML] Exercise redox biochemistry: conceptual, methodological and technical recommendations
Exercise redox biochemistry is of considerable interest owing to its translational value in
health and disease. However, unaddressed conceptual, methodological and technical …
health and disease. However, unaddressed conceptual, methodological and technical …
Exploring the unmapped cysteine redox proteoform landscape
JN Cobley - American Journal of Physiology-Cell …, 2024 - journals.physiology.org
Cysteine redox proteoforms define the diverse molecular states that proteins with cysteine
residues can adopt. A protein with one cysteine residue must adopt one of two binary …
residues can adopt. A protein with one cysteine residue must adopt one of two binary …
[HTML][HTML] Ten “Cheat Codes” for Measuring Oxidative Stress in Humans
Formidable and often seemingly insurmountable conceptual, technical, and methodological
challenges hamper the measurement of oxidative stress in humans. For instance, fraught …
challenges hamper the measurement of oxidative stress in humans. For instance, fraught …
Dynamic proteome profiling of individual proteins in human skeletal muscle after a high-fat diet and resistance exercise
It is generally accepted that muscle adaptation to resistance exercise (REX) training is
underpinned by contraction-induced, increased rates of protein synthesis and dietary protein …
underpinned by contraction-induced, increased rates of protein synthesis and dietary protein …
Principles for integrating reactive species into in vivo biological processes: examples from exercise physiology
The equivocal role of reactive species and redox signaling in exercise responses and
adaptations is an example clearly showing the inadequacy of current redox biology research …
adaptations is an example clearly showing the inadequacy of current redox biology research …
Quantification of exercise‐regulated ubiquitin signaling in human skeletal muscle identifies protein modification cross talk via NEDDylation
The maintenance of muscle function is extremely important for whole body health and
exercise is essential to this process. The ubiquitin‐proteasome system (UPS) is required for …
exercise is essential to this process. The ubiquitin‐proteasome system (UPS) is required for …