Zinc coordination complexes as anticancer agents

M Pellei, F Del Bello, M Porchia, C Santini - Coordination Chemistry …, 2021 - Elsevier
Zinc, present in all forms of life, is an essential element for humans. It is one of the most
abundant metals in our body. Because of its importance, any malfunctions of its homeostasis …

Zinc complexes with nitrogen donor ligands as anticancer agents

M Porchia, M Pellei, F Del Bello, C Santini - Molecules, 2020 - mdpi.com
The search for anticancer metal-based drugs alternative to platinum derivatives could not
exclude zinc derivatives due to the importance of this metal for the correct functioning of the …

Anticancer and DNA binding studies of potential amino acids based quinazolinone analogs: Synthesis, SAR and molecular docking

KP Rakesh, HK Kumara, HM Manukumar… - Bioorganic …, 2019 - Elsevier
A novel series of amino acids conjugated quinazolinone-Schiff's bases were synthesized
and screened for their in vitro anticancer activity and validated by molecular docking and …

Cyclen-based artificial nucleases: Three decades of development (1989–2022). Part a–Hydrolysis of phosphate esters

MD Tomczyk, N Kuźnik, K Walczak - Coordination Chemistry Reviews, 2023 - Elsevier
The first part of the review summarizes more than three decades of research on cyclen
complexes, with a particular focus on complexes that exhibit hydrolytic (or transesterification) …

Coordination compounds of biogenic metals as cytotoxic agents in cancer therapy

DA Guk, OO Krasnovskaya… - Russian Chemical …, 2021 - iopscience.iop.org
The review summarizes the data on the structures and methods for the synthesis of
compounds with anticancer activity based on biogenic metals, which can replace platinum …

Novel zinc (II)− curcumin molecular probes bearing berberine and jatrorrhizine derivatives as potential mitochondria-targeting anti-neoplastic drugs

SH Zhang, ZF Wang, H Tan - European Journal of Medicinal Chemistry, 2022 - Elsevier
Berberine and jatrorrhizine are major bioactive components that are emerging as potential
anti-cancer drugs. However, no zinc (II)–berberine/jatrorrhizine–curcumin compounds have …

A review on zinc, cadmium, and mercury complexes with anticancer activity

ES Moghadam, Z Emamgholipour, A Foroumadi… - Inorganic Chemistry …, 2024 - Elsevier
Over the last few years, there has been a surge in interest surrounding the exploration of the
therapeutic benefits of metal-based complexes because of their great potential in treating a …

Synthesis, characterization and anticancer studies of bis-(N-methyl-1-phenyldithiocarbamato) Cu (II), Zn (II), and Pt (II) complexes: single crystal X-ray structure of the …

FP Andrew, PA Ajibade - Journal of Coordination Chemistry, 2018 - Taylor & Francis
Abstract Cu (II), Pt (II), and Zn (II) complexes of N-methyl-1-phenyldithiocarbamate were
synthesized and characterized by FTIR, NMR, UV-visible spectroscopy and elemental …

Effective anticancer activities of an acyclic symmetrical compartmental Schiff base ligand and its Co (II), Cu (II) and Zn (II) complexes against the human leukemia cell …

L Saghatforoush, K Moeini, SA Hosseini-Yazdi… - Polyhedron, 2019 - Elsevier
Syntheses of new N 2 O 5 donor type compartmental Schiff base ligand, 2, 2′-((((((2-
hydroxypropane-1, 3-diyl) bis (oxy)) bis (2, 1-phenylene)) bis (methylene)) bis …

Novel terpestacin derivatives with l-amino acid residue as anticancer agents against U87MG-derived glioblastoma stem cells

S Liao, N Yuk, YJ Kim, H Xu, X Li, L Wang, Y Liu… - Bioorganic …, 2023 - Elsevier
Based on the natural product terpestacin, seventeen derivatives (1–17) with various l-amino
acid side chains were designed and synthesized. Their anticancer activities against U87MG …