Congenital Diaphragmatic hernia (CDH) is a condition characterized by a defect in the
diaphragm leading to protrusion of abdominal contents into the thoracic cavity interfering …

The transition from a fetus to a newborn is the most complex physiologic adaptation that
occurs in human experience. Before medicalization of delivery, the transition had to occur …

Objectives: The American College of Critical Care Medicine provided 2002 and 2007
guidelines for hemodynamic support of newborn and pediatric septic shock. Provide the …

Background: The Institute of Medicine calls for the use of clinical guidelines and practice
parameters to promote “best practices” and to improve patient outcomes. Objective: 2007 …

Pathophysiology and Management of Persistent Pulmonary Hypertension of the Newborn -
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Persistent pulmonary hypertension of the newborn (PPHN) is a syndrome of failed
circulatory adaptation at birth, seen in about 2/1000 live born infants. While it is mostly seen …

Objective Variable management practices complicate the identification of optimal strategies
for infants with congenital diaphragmatic hernia (CDH). This review critically appraises the …

Persistent pulmonary hypertension of the newborn (PPHN) is a significant clinical problem
characterized by refractory and severe hypoxemia secondary to elevated pulmonary …

Inhaled nitric oxide (iNO) is approved for use in persistent pulmonary hypertension of the
newborn (PPHN) but does not lead to sustained improvement in oxygenation in one-third of …

Hemodynamic disturbance in the sick neonate is common, highly diverse in underlying
pathophysiology and dynamic. Dysregulated systemic and cerebral blood flow is …