Neuroplasticity and depression: Rewiring the brain's networks through pharmacological therapy

I Rădulescu, AM Drăgoi… - Experimental and …, 2021 - spandidos-publications.com
In modern society, depression is one of the most common mental illness; however, its
pathophysiology is not yet fully understood. A great body of evidence suggests that …

Nanotechnological approaches to enhance the potential of α-lipoic acid for application in the clinic

C Bellini, F Mancin, E Papini, R Tavano - Antioxidants, 2024 - mdpi.com
α-lipoic acid is a naturally occurring compound with potent antioxidant properties that helps
protect cells and tissues from oxidative stress. Its incorporation into nanoplatforms can affect …

Comprehensive Analysis of Novel Synergistic Antioxidant Formulations: Insights into Pharmacotechnical, Physical, Chemical, and Antioxidant Properties

SM Neacșu, M Mititelu, EA Ozon, AM Musuc, IDM Iuga… - Pharmaceuticals, 2024 - mdpi.com
(1) Background: Oxidative stress plays a pivotal role in the pathogenesis of various
diseases, including neurodegenerative disorders, cardiovascular diseases, cancer, and …

Physicochemical compatibility studies of triclosan and flurbiprofen with excipients of pharmaceutical formulation using binary, ternary, and multi-combination approach

N Aminu, SY Chan, MA Mumuni, NM Umar… - Future Journal of …, 2021 - Springer
Background The aim of the study was to evaluate the suitability of triclosan (TCS) and
flurbiprofen (FLB) with poly-ε-caprolactone (PCL), chitosan (CS), and Kolliphor® P188 (KP) …

Potential of plant-derived compounds in preventing and reversing Organ Fibrosis and the underlying mechanisms

PS Azeredo, D Fan, EA Murphy, WE Carver - Cells, 2024 - mdpi.com
Increased production of extracellular matrix is a necessary response to tissue damage and
stress. In a normal healing process, the increase in extracellular matrix is transient. In some …

[PDF][PDF] Study regarding a new extended-release calcium ascorbate and hesperidin solid oral formulation

AL Pop, P Henteș, MA Pali, L Oșanu, AM Ciobanu… - Farmacia, 2022 - researchgate.net
Vitamin C is indispensable for the normal functioning of the most important biological
processes in the human body and plays an essential role in the immune response to stress …

[HTML][HTML] Design and evaluation of orally dispersible tablets containing amlodipine inclusion complexes in hydroxypropyl-β-cyclodextrin and methyl-β-cyclodextrin

M Novac, AM Musuc, EA Ozon, I Sarbu, MA Mitu… - Materials, 2022 - mdpi.com
The development of new orally dispersible tablets containing amlodipine (AML) inclusion
complexes in hydroxypropyl-β-cyclodextrin (HP-β-CD) and in methyl-β-cyclodextrin (Me-β …

[HTML][HTML] Manufacturing and assessing the new orally disintegrating tablets, containing nimodipine-hydroxypropyl-β-cyclodextrin and nimodipine-methyl-β-cyclodextrin …

M Novac, AM Musuc, EA Ozon, I Sarbu, MA Mitu… - Molecules, 2022 - mdpi.com
The aim of the present study was to manufacture new orally disintegrating tablets containing
nimodipine–hydroxypropyl-β-cyclodextrin and nimodipine–methyl-β-cyclodextrin inclusion …

[HTML][HTML] Formation and Physico-Chemical Evaluation of Nifedipine-hydroxypropyl-β-cyclodextrin and Nifedipine-methyl-β-cyclodextrin: The Development of …

EA Ozon, M Novac, D Gheorghe, AM Musuc, MA Mitu… - Pharmaceuticals, 2022 - mdpi.com
The novelty in this study is the development of new orodispersible tablets containing
nifedipine (NIF) as the active ingredient. Initially, the formation of inclusion complexes …

[HTML][HTML] Pharmacotechnical, Physico-Chemical, and Antioxidant Evaluation of Newly Developed Capsule Formulations

EA Ozon, IDM Iuga, M Mititelu, AM Musuc… - International Journal of …, 2023 - mdpi.com
The excess of free radicals causes numerous imbalances in the body that lead to premature
aging, the degradation of internal structures, and the appearance of numerous pathologies …