The versatility in the applications of dithiocarbamates
TO Ajiboye, TT Ajiboye, R Marzouki… - International Journal of …, 2022 - mdpi.com
Dithiocarbamate ligands have the ability to form stable complexes with transition metals, and
this chelating ability has been utilized in numerous applications. The complexes have also …
this chelating ability has been utilized in numerous applications. The complexes have also …
An insight into medicinal attributes of dithiocarbamates: Bird's eye view
SD Shinde, AP Sakla, N Shankaraiah - Bioorganic chemistry, 2020 - Elsevier
Dithiocarbamates are considered as an important motif owing to its extensive biological
applications in medicinal chemistry. The synthesis of this framework can easily be achieved …
applications in medicinal chemistry. The synthesis of this framework can easily be achieved …
The revival of dithiocarbamates: from pesticides to innovative medical treatments
L Kaul, R Süss, A Zannettino, K Richter - IScience, 2021 - cell.com
Dithiocarbamates (DTCs) have been used for various applications, including as hardening
agents in rubber manufacturing, as fungicide in agriculture, and as medications to treat …
agents in rubber manufacturing, as fungicide in agriculture, and as medications to treat …
Steroids interfere with human carbonic anhydrase activity by using alternative binding mechanisms
A Nocentini, A Bonardi, P Gratteri, B Cerra… - Journal of Enzyme …, 2018 - Taylor & Francis
Bile acids have been shown to inhibit human (h) carbonic anhydrases (CA, EC 4.2. 1.1)
along the gastrointestinal tract, including hCA II. The elucidation of the hormonal inhibition …
along the gastrointestinal tract, including hCA II. The elucidation of the hormonal inhibition …
Selenium-analogs based on natural sources as cancer-associated carbonic anhydrase isoforms IX and XII inhibitors
N Astrain-Redin, N Paoletti, D Plano… - Journal of enzyme …, 2023 - Taylor & Francis
In the relentless search for new cancer treatments, organoselenium compounds, and
carbonic anhydrase (CA) inhibitors have emerged as promising drug candidates. CA …
carbonic anhydrase (CA) inhibitors have emerged as promising drug candidates. CA …
[HTML][HTML] Anti-Malassezia Drug Candidates Based on Virulence Factors of Malassezia-Associated Diseases
M Billamboz, S Jawhara - Microorganisms, 2023 - mdpi.com
Malassezia is a lipophilic unicellular fungus that is able, under specific conditions, to cause
severe cutaneous and systemic diseases in predisposed subjects. This review is divided …
severe cutaneous and systemic diseases in predisposed subjects. This review is divided …
[HTML][HTML] Selective Inhibition of Helicobacter pylori Carbonic Anhydrases by Carvacrol and Thymol Could Impair Biofilm Production and the Release of Outer …
R Grande, S Carradori, V Puca, I Vitale… - International journal of …, 2021 - mdpi.com
Helicobacter pylori, a Gram-negative neutrophilic pathogen, is the cause of chronic gastritis,
peptic ulcers, and gastric cancer in humans. Current therapeutic regimens suffer from an …
peptic ulcers, and gastric cancer in humans. Current therapeutic regimens suffer from an …
A highlight on the inhibition of fungal carbonic anhydrases as drug targets for the antifungal armamentarium
CT Supuran, C Capasso - International Journal of Molecular Sciences, 2021 - mdpi.com
Carbon dioxide (CO2), a vital molecule of the carbon cycle, is a critical component in living
organisms' metabolism, performing functions that lead to the building of compounds …
organisms' metabolism, performing functions that lead to the building of compounds …
A comparative study of diaryl urea molecules with and without sulfonamide group on Carbonic anhydrase IX and XII inhibition and its consequence on breast cancer …
J Debnath, D Keshamasetthy, J Combs, K Leon… - Bioorganic …, 2024 - Elsevier
To investigate the intrinsic relation between carbonic anhydrase inhibition and anticancer
activity, we have prepared four sets of diaryl urea molecules and tested for the inhibition of …
activity, we have prepared four sets of diaryl urea molecules and tested for the inhibition of …
Benzoxaboroles as efficient inhibitors of the β-carbonic anhydrases from pathogenic fungi: activity and modeling study
A Nocentini, R Cadoni, S Del Prete… - ACS Medicinal …, 2017 - ACS Publications
A series of 6-substituted benzoxaboroles were investigated as inhibitors of the β-class
carbonic anhydrase from three pathogenic fungi (Cryptococcus neoformans, Candida …
carbonic anhydrase from three pathogenic fungi (Cryptococcus neoformans, Candida …