Brain waste removal system and sleep: photobiomodulation as an innovative strategy for night therapy of brain diseases

O Semyachkina-Glushkovskaya, I Fedosov… - International journal of …, 2023‏ - mdpi.com
Emerging evidence suggests that an important function of the slee** brain is the removal
of wastes and toxins from the central nervous system (CNS) due to the activation of the brain …

[HTML][HTML] The crosstalk between the blood–brain barrier dysfunction and neuroinflammation after General Anaesthesia

X Yang, X Chen - Current issues in molecular biology, 2022‏ - mdpi.com
As we know, with continuous medical progress, the treatment of many diseases can be
conducted via surgery, which often relies on general anaesthesia for its satisfactory …

[HTML][HTML] Factors predisposing to humoral autoimmunity against brain-antigens in health and disease: Analysis of 49 autoantibodies in over 7000 subjects

VD Gastaldi, JBH Wilke, CA Weidinger, C Walter… - Brain, Behavior, and …, 2023‏ - Elsevier
Background Circulating autoantibodies (AB) against brain-antigens, often deemed
pathological, receive increasing attention. We assessed predispositions and …

Reduced malignant glioblastoma recurrence post-resection through the anti-CD47 antibody and Temozolomide co-embedded in-situ hydrogel system

L Ye, W Lv, W He, S Li, Z Min, L Gong, Q Zhang… - Journal of Controlled …, 2023‏ - Elsevier
Infiltrative glioma growth makes surgical excision incomplete, and the residual tumor cells
proliferate rapidly. Residual glioma cells evade phagocytosis by macrophages through …

[HTML][HTML] Detrimental Effects of ApoE ε4 on Blood–Brain Barrier Integrity and Their Potential Implications on the Pathogenesis of Alzheimer's Disease

K Kirchner, L Garvert, L Kühn, S Bonk, HJ Grabe… - Cells, 2023‏ - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease representing the most
common type of dementia in older adults. The major risk factors include increased age …

The Effects of Propofol on a Human in vitro Blood-Brain Barrier Model

JM Hughes, OR Neese, DD Bieber… - Frontiers in Cellular …, 2022‏ - frontiersin.org
Background Recently, the safety of repeated and lengthy anesthesia administration has
been called into question, a subset of these animal studies demonstrated that anesthetics …

Effects of volatile anesthetics versus ketamine on blood-brain barrier permeability via lipid-mediated alterations of endothelial cell membranes

B Noorani, EA Chowdhury, F Alqahtani, Y Ahn… - The Journal of …, 2023‏ - Elsevier
The purpose of this study was to investigate the effects of the volatile anesthetic agents
isoflurane and sevoflurane, at clinically relevant concentrations, on the fluidity of lipid …

The Acute Impact of Propofol on Blood–Brain Barrier Integrity in Mice

E Nozohouri, Y Ahn, S Zoubi, D Patel, SR Archie… - Pharmaceutical …, 2024‏ - Springer
Purpose We investigated whether short term infusion of propofol, a highly lipophilic agonist
at GABAA receptors, which is in widespread clinical use as anesthetic and sedative, affects …

Mesoscopic map** of hemodynamic responses and neuronal activity during pharmacologically induced interictal spikes in awake and anesthetized mice

J Li, F Yang, F Zhan, J Estin, A Iyer… - Journal of Cerebral …, 2024‏ - journals.sagepub.com
Imaging hemodynamic responses to interictal spikes holds promise for presurgical epilepsy
evaluations. Understanding the hemodynamic response function is crucial for accurate …

[HTML][HTML] Effects of blood-brain barrier opening using ultrasound on tauopathies: A systematic review

A Géraudie, P De Rossi, M Canney… - Journal of Controlled …, 2025‏ - Elsevier
Blood-brain barrier opening with ultrasound can potentiate drug efficacy in the treatment of
brain pathologies and also provides therapeutic effects on its own. It is an innovative tool to …