Editing the central nervous system through CRISPR/Cas9 systems

A Cota-Coronado, NF Díaz-Martínez… - Frontiers in molecular …, 2019 - frontiersin.org
The translational gap to treatments based on gene therapy has been reduced in recent
years because of improvements in gene editing tools, such as the CRISPR/Cas9 system and …

Vector enabled CRISPR gene editing–A revolutionary strategy for targeting the diversity of brain pathologies

H Forgham, L Liu, J Zhu, I Javed, W Cai, R Qiao… - Coordination chemistry …, 2023 - Elsevier
Brain pathologies are considered one of the greatest contributors of death and disability
worldwide. Neurodegenerative Alzheimer's disease is the second leading cause of death in …

[BOOK][B] Basal Forebrain Cholinergic Neurons in Down Syndrome

JL Martinez - 2024 - search.proquest.com
Down syndrome (DS), or trisomy 21 (T21), is both a complex neurodevelopmental and
neurodegenerative disorder. DS is characterized by altered neuronal cortical development …

[PDF][PDF] Терапия болезни Альцгеймера: вызовы и перспективы

МА Орлов - Успехи геронтологии, 2019 - researchgate.net
В настоящем обзоре рассмотрены как нашедшие применение в клинике, так и
находящиеся на стадии разработки и внедрения способы терапии болезни …

[PDF][PDF] 罗氏沼虾性别相关基因研究进展及其单性化养殖现状

姜建萍, 袁翔, 邱庆庆, 黄光华, 蒋钦杨, 杨秀荣… - 南方农业 …, 2019 - nfnyxb.boyuancb.com
罗氏沼虾(Macrobrachium rosenbergii) 具有生长快, 养殖周期短, 营养价值高等优点,
是我国主要的淡水虾养殖品种, 在生长性能方面表现出性别两态性: 同龄雌, 雄虾个体的大小 …

Enzyme Inhibition Applications in Treatment of Neurological Disorders

D Lokapriya, PK PK - Enzyme Inhibition-Environmental and …, 2020 - benthamdirect.com
Enzyme inhibitors are widely prescribed drugs for many diseases including neurological
disorders and today most of the drugs are enzyme inhibitors and are in the clinical/pre …

Research progress of sex-related genes and research status of monosex culture in Macrobrachium rosenbergii: a review.

JJP Jiang Jian**, YX Yuan **ang… - 2019 - cabidigitallibrary.org
Giant freshwater prawn (Macrobrachium rosenbergii) as an important freshwater prawn has
become one of the leading varieties of freshwater aquaculture in China due to its quicker …