Reactive oxygen species and cancer paradox: to promote or to suppress?

S Galadari, A Rahman, S Pallichankandy… - Free Radical Biology …, 2017 - Elsevier
Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …

Capsicum annuum (hot pepper): An ancient Latin‐American crop with outstanding bioactive compounds and nutraceutical potential. A review

T Hernández‐Pérez, MR Gómez‐García… - … Reviews in Food …, 2020 - Wiley Online Library
Hot pepper (Capsicum annuum) fruits, usually termed as chili, have been used since ancient
times as food vegetables, flavoring ingredients, natural colorants, and in traditional …

Small molecules regulating reactive oxygen species homeostasis for cancer therapy

J Zhang, D Duan, ZL Song, T Liu… - Medicinal Research …, 2021 - Wiley Online Library
Elevated intracellular reactive oxygen species (ROS) and antioxidant defense systems have
been recognized as one of the hallmarks of cancer cells. Compared with normal cells …

Anticancer properties of capsaicin against human cancer

R Clark, SH Lee - Anticancer research, 2016 - ar.iiarjournals.org
There is persuasive epidemiological and experimental evidence that dietary phytochemicals
have anticancer activity. Capsaicin is a bioactive phytochemical abundant in red and chili …

Kimchi and other widely consumed traditional fermented foods of Korea: a review

JK Patra, G Das, S Paramithiotis, HS Shin - Frontiers in microbiology, 2016 - frontiersin.org
Different types of fermented foods such as chongkukjang, doenjang, ganjang, gochujang,
and kimchi are plentifully available and widely consumed in north eastern Asian countries …

Ablation of sensory neurons in a genetic model of pancreatic ductal adenocarcinoma slows initiation and progression of cancer

JL Saloman, KM Albers, D Li… - Proceedings of the …, 2016 - National Acad Sciences
Pancreatic ductal adenocarcinoma (PDAC) is characterized by an exuberant inflammatory
desmoplastic response. The PDAC microenvironment is complex, containing both pro-and …

Mechanisms and clinical uses of capsaicin

SK Sharma, AS Vij, M Sharma - European journal of pharmacology, 2013 - Elsevier
Capsaicin is the active ingredient of chili peppers and gives them the characteristic pungent
flavor. Understanding the actions of capsaicin led to the discovery of its receptor, transient …

ROS‐mediated cancer cell killing through dietary phytochemicals

S NavaneethaKrishnan, JL Rosales… - Oxidative medicine and …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) promote carcinogenesis by inducing genetic mutations,
activating oncogenes, and raising oxidative stress, which all influence cell proliferation …

Capsaicin: From plants to a cancer-suppressing agent

AM Chapa-Oliver, L Mejía-Teniente - Molecules, 2016 - mdpi.com
Capsaicinoids are plant secondary metabolites, capsaicin being the principal responsible
for the pungency of chili peppers. It is biosynthesized through two pathways involved in …

[HTML][HTML] Rhaponticin suppresses osteosarcoma through the inhibition of PI3K-Akt-mTOR pathway

S Mickymaray, FA Alfaiz, A Paramasivam… - Saudi journal of …, 2021 - Elsevier
Osteosarcoma is the frequent pediatric bone cancer where pediatric osteosarcoma
incidences are more than 10% within the population. Most of the patients with osteosarcoma …