Single-cell transcriptomics has broadened our understanding of cellular diversity and gene
expression dynamics in healthy and diseased tissues. Recently, spatial transcriptomics has …

Although immunotherapy has revolutionized solid tumor treatment, durable responses in
gastric cancer (GC) remain limited. The heterogeneous tumor microenvironment (TME) …

Spatial transcriptomics (ST) methods unlock molecular mechanisms underlying tissue
development, homeostasis, or disease. However, there is a need for easy-to-use, high …

Spatially resolved gene expression profiling provides insight into tissue organization and
cell–cell crosstalk; however, sequencing-based spatial transcriptomics (ST) lacks single-cell …

Spatial transcriptomics enables interrogating the molecular composition of tissue with ever-
increasing resolution and sensitivity. However, costs, rapidly evolving technology, and lack …

Spatially resolved transcriptomics (SRT) studies are becoming increasingly common and
large, offering unprecedented opportunities in map** complex tissue structures and …

Recent advances in subcellular imaging transcriptomics platforms have enabled high-
resolution spatial map** of gene expression, while also introducing significant analytical …

The growing availability of single-cell and spatially resolved transcriptomics has led to the
development of many approaches to infer cell–cell communication, each capturing only a …

Spatial transcriptomics measures in situ gene expression at millions of locations within a
tissue, hitherto with some trade-off between transcriptome depth, spatial resolution and …

Solid tumours comprise many different cell types organized in spatially structured
arrangements, with substantial intratumour and intertumour heterogeneity. Advances in …