Ru (II) compounds: next-generation anticancer metallotherapeutics?
Metal based therapeutics are a precious class of drugs in oncology research that include
examples of theranostic drugs, which are active in both diagnostic, specifically imaging, and …
examples of theranostic drugs, which are active in both diagnostic, specifically imaging, and …
Photocleavable Ortho-Nitrobenzyl-Protected DNA Architectures and Their Applications
This review article introduces mechanistic aspects and applications of photochemically
deprotected ortho-nitrobenzyl (ONB)-functionalized nucleic acids and their impact on …
deprotected ortho-nitrobenzyl (ONB)-functionalized nucleic acids and their impact on …
Plight of CORMs: The unreliability of four commercially available CO-releasing molecules, CORM-2, CORM-3, CORM-A1, and CORM-401, in studying CO biology
Carbon monoxide (CO) is an endogenously produced gaseous signaling molecule with
demonstrated pharmacological effects. In studying CO biology, three delivery forms have …
demonstrated pharmacological effects. In studying CO biology, three delivery forms have …
Recent advancements in coordination compounds and their potential clinical application in the management of diseases: An up-to-date review
Coordination compounds-based drugs are crucial in targeting various diseases due to their
distinct structural order. They also show a significant role in biological systems, including …
distinct structural order. They also show a significant role in biological systems, including …
Lysosome-targeted chemotherapeutics: half-sandwich ruthenium (II) complexes that are selectively toxic to cancer cells
Z Tian, J Li, S Zhang, Z Xu, Y Yang, D Kong… - Inorganic …, 2018 - ACS Publications
Poor selectivity between cancer cells and normal cells is one of the major limitations of
cancer chemotherapy. Lysosome-targeted ruthenium-based complexes target tumor cells …
cancer chemotherapy. Lysosome-targeted ruthenium-based complexes target tumor cells …
Novel indole-thiazole and indole-thiazolidinone derivatives as DNA groove binders
JEF Alves, JF de Oliveira, TRC de Lima Souza… - International Journal of …, 2021 - Elsevier
In this study, we report the synthesis of eight novel indole-thiazole and indole-thiazolidinone
derivatives, as well as their ability to interact with DNA, analysed through the UV–vis …
derivatives, as well as their ability to interact with DNA, analysed through the UV–vis …
Energetically significant unconventional π-π contacts involving fumarate in a novel coordination polymer of Zn (II): In-vitro anticancer evaluation and theoretical studies
A new fumarato bridged Zn (II) coordination polymer viz. catena [μ-fumaratobis (3, 5-
dimethylpyrazole) zinc (II) trihydrate],{[Zn 2 (μ-fum) 2 (Hdmpz) 4]· 3H 2 O} n (1)(where, fum …
dimethylpyrazole) zinc (II) trihydrate],{[Zn 2 (μ-fum) 2 (Hdmpz) 4]· 3H 2 O} n (1)(where, fum …
A novel series of pyrazole-platinum (II) complexes as potential anti-cancer agents that induce cell cycle arrest and apoptosis in breast cancer cells
R Czarnomysy, A Surażyński… - Journal of enzyme …, 2018 - Taylor & Francis
Six novel compounds of platinum (II) with pyrazole derivatives PtPz1–PtPz6 were
synthesised and characterised (PtPz1-[Pt2N-hydroksymethyl-3, 5-dimethylpyrazole4 …
synthesised and characterised (PtPz1-[Pt2N-hydroksymethyl-3, 5-dimethylpyrazole4 …
Design, synthesis, spectral characterization, DNA binding, photo cleavage and antibacterial studies of transition metal complexes of benzothiazole Schiff base
NN Rao, K Gopichand, R Nagaraju, AM Ganai… - Chemical Data …, 2020 - Elsevier
In the present work, a series of Benzothiazole based Schiff base ligand 2-((E)-(6-
ethoxybenzo [d] thiazol-2-ylimino) methyl)-4-nitrophenol and their Cu (II), Co (II), Ni (II), Zn …
ethoxybenzo [d] thiazol-2-ylimino) methyl)-4-nitrophenol and their Cu (II), Co (II), Ni (II), Zn …
Synthesis, characterization and DNA binding properties of Schiff base derivatives and Ru (II) complexes
FT Elmali - Journal of Molecular Structure, 2022 - Elsevier
Schiff base ligands were synthesized by condensation of 5-amino-1, 10-phenanthroline with
4-hydroxybenzaldehyde (L1) and decanal (L2). Ruthenium (II) metal complexes (L1-Ru (II) …
4-hydroxybenzaldehyde (L1) and decanal (L2). Ruthenium (II) metal complexes (L1-Ru (II) …