Ru (II) compounds: next-generation anticancer metallotherapeutics?

S Thota, DA Rodrigues, DC Crans… - Journal of medicinal …, 2018 - ACS Publications
Metal based therapeutics are a precious class of drugs in oncology research that include
examples of theranostic drugs, which are active in both diagnostic, specifically imaging, and …

Photocleavable Ortho-Nitrobenzyl-Protected DNA Architectures and Their Applications

MP O'Hagan, Z Duan, F Huang, S Laps, J Dong… - Chemical …, 2023 - ACS Publications
This review article introduces mechanistic aspects and applications of photochemically
deprotected ortho-nitrobenzyl (ONB)-functionalized nucleic acids and their impact on …

Plight of CORMs: The unreliability of four commercially available CO-releasing molecules, CORM-2, CORM-3, CORM-A1, and CORM-401, in studying CO biology

N Bauer, Z Yuan, X Yang, B Wang - Biochemical Pharmacology, 2023 - Elsevier
Carbon monoxide (CO) is an endogenously produced gaseous signaling molecule with
demonstrated pharmacological effects. In studying CO biology, three delivery forms have …

Recent advancements in coordination compounds and their potential clinical application in the management of diseases: An up-to-date review

VK Singh, VK Singh, A Mishra, AA Singh, G Prasad… - Polyhedron, 2023 - Elsevier
Coordination compounds-based drugs are crucial in targeting various diseases due to their
distinct structural order. They also show a significant role in biological systems, including …

Lysosome-targeted chemotherapeutics: half-sandwich ruthenium (II) complexes that are selectively toxic to cancer cells

Z Tian, J Li, S Zhang, Z Xu, Y Yang, D Kong… - Inorganic …, 2018 - ACS Publications
Poor selectivity between cancer cells and normal cells is one of the major limitations of
cancer chemotherapy. Lysosome-targeted ruthenium-based complexes target tumor cells …

Novel indole-thiazole and indole-thiazolidinone derivatives as DNA groove binders

JEF Alves, JF de Oliveira, TRC de Lima Souza… - International Journal of …, 2021 - Elsevier
In this study, we report the synthesis of eight novel indole-thiazole and indole-thiazolidinone
derivatives, as well as their ability to interact with DNA, analysed through the UV–vis …

Energetically significant unconventional π-π contacts involving fumarate in a novel coordination polymer of Zn (II): In-vitro anticancer evaluation and theoretical studies

A Gogoi, A Das, A Frontera, AK Verma… - Inorganica Chimica …, 2019 - Elsevier
A new fumarato bridged Zn (II) coordination polymer viz. catena [μ-fumaratobis (3, 5-
dimethylpyrazole) zinc (II) trihydrate],{[Zn 2 (μ-fum) 2 (Hdmpz) 4]· 3H 2 O} n (1)(where, fum …

A novel series of pyrazole-platinum (II) complexes as potential anti-cancer agents that induce cell cycle arrest and apoptosis in breast cancer cells

R Czarnomysy, A Surażyński… - Journal of enzyme …, 2018 - Taylor & Francis
Six novel compounds of platinum (II) with pyrazole derivatives PtPz1–PtPz6 were
synthesised and characterised (PtPz1-[Pt2N-hydroksymethyl-3, 5-dimethylpyrazole4 …

Design, synthesis, spectral characterization, DNA binding, photo cleavage and antibacterial studies of transition metal complexes of benzothiazole Schiff base

NN Rao, K Gopichand, R Nagaraju, AM Ganai… - Chemical Data …, 2020 - Elsevier
In the present work, a series of Benzothiazole based Schiff base ligand 2-((E)-(6-
ethoxybenzo [d] thiazol-2-ylimino) methyl)-4-nitrophenol and their Cu (II), Co (II), Ni (II), Zn …

Synthesis, characterization and DNA binding properties of Schiff base derivatives and Ru (II) complexes

FT Elmali - Journal of Molecular Structure, 2022 - Elsevier
Schiff base ligands were synthesized by condensation of 5-amino-1, 10-phenanthroline with
4-hydroxybenzaldehyde (L1) and decanal (L2). Ruthenium (II) metal complexes (L1-Ru (II) …