Dietary (poly) phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases

D Del Rio, A Rodriguez-Mateos… - Antioxidants & redox …, 2013 - liebertpub.com
Human intervention trials have provided evidence for protective effects of various (poly)
phenol-rich foods against chronic disease, including cardiovascular disease …

[HTML][HTML] Resveratrol: From enhanced biosynthesis and bioavailability to multitargeting chronic diseases

N Pannu, A Bhatnagar - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Resveratrol, a phytoalexin with a wide range of pharmacological properties is synthesised
by plants in response to stress, injury, infection or UV radiations. As it is a secondary …

Health effects of resveratrol: Results from human intervention trials

SL Ramírez-Garza, EP Laveriano-Santos… - Nutrients, 2018 - mdpi.com
The effect of resveratrol (RV) intake has been reviewed in several studies performed in
humans with different health status. The purpose of this review is to summarize the results of …

Resveratrol and clinical trials: the crossroad from in vitro studies to human evidence

J Tomé-Carneiro, M Larrosa… - Current …, 2013 - benthamdirect.com
Resveratrol (3, 5, 4'-trihydroxy-trans-stilbene) is a non-flavonoid polyphenol that may be
present in a limited number of foodstuffs such as grapes and red wine. Resveratrol has been …

[HTML][HTML] Lifespan and healthspan extension by resveratrol

KS Bhullar, BP Hubbard - Biochimica et Biophysica Acta (BBA)-Molecular …, 2015 - Elsevier
A number of small molecules with the ability to extend the lifespan of multiple organisms
have recently been discovered. Resveratrol, amongst the most prominent of these, has …

The nutraceutical bioavailability classification scheme: classifying nutraceuticals according to factors limiting their oral bioavailability

DJ McClements, F Li, H **ao - Annual review of food science …, 2015 - annualreviews.org
The oral bioavailability of a health-promoting dietary component (nutraceutical) may be
limited by various physicochemical and physiological phenomena: liberation from food …

Resveratrol bioavailability and toxicity in humans

CH Cottart, V Nivet‐Antoine… - Molecular nutrition & …, 2010 - Wiley Online Library
Numerous data are now available on the beneficial properties of the polyphenolic
compound resveratrol including its anti‐inflammatory and antitumor effects. However, few …

What is new for an old molecule? Systematic review and recommendations on the use of resveratrol

O Vang, N Ahmad, CA Baile, JA Baur, K Brown… - PloS one, 2011 - journals.plos.org
Background Resveratrol is a natural compound suggested to have beneficial health effects.
However, people are consuming resveratrol for this reason without having the adequate …

Enhancing the bioavailability of resveratrol by combining it with piperine

JJ Johnson, M Nihal, IA Siddiqui… - Molecular nutrition & …, 2011 - Wiley Online Library
Abstract Scope: Resveratrol (3, 5, 4′‐trihydroxystilbene) is a phytoalexin shown to possess
a multitude of health‐promoting properties in pre‐clinical studies. However, the poor in vivo …

Pharmacokinetic and safety profile of trans‐resveratrol in a rising multiple‐dose study in healthy volunteers

L Almeida, M Vaz‐da‐Silva, A Falcão… - Molecular nutrition & …, 2009 - Wiley Online Library
This was a double‐blind, randomised, placebo‐controlled study to investigate the
pharmacokinetics and safety of trans‐resveratrol. In four groups of ten healthy adult subjects …