A major goal of evolutionary genetics is to understand the genetic processes that give rise to
phenotypic diversity in multicellular organisms. Alternative splicing generates multiple …

The target of rapamycin (TOR), discovered 30 years ago, is a highly conserved
serine/threonine protein kinase that plays a central role in regulating cell growth and …

Snakebite envenoming is a major global public health concern for which improved therapies
are urgently needed. The antigenic diversity present in snake venom toxins from various …

Oxford Nanopore Technologies'(ONT) long read sequencers offer access to longer DNA
fragments than previous sequencer generations, at the cost of a higher error rate. While …

Directed evolution aims to expedite the natural evolution process of biological molecules
and systems in a test tube through iterative rounds of gene diversifications and library …

The potential for future coronavirus outbreaks highlights the need to broadly target this
group of pathogens. We used an epitope-agnostic approach to identify six monoclonal …

Phycobilisome (PBS) structures are elaborate antennae in cyanobacteria and red algae,.
These large protein complexes capture incident sunlight and transfer the energy through a …

Understanding the molecular basis for immune recognition of SARS-CoV-2 spike
glycoprotein antigenic sites will inform the development of improved therapeutics. We …

Transposition has a key role in resha** genomes of all living organisms. Insertion
sequences of IS200/IS605 and IS607 families are among the simplest mobile genetic …

The unprecedented pandemic of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) is threatening global health. The virus emerged in late 2019 and can cause a …