Oligosaccharides are the ubiquitous molecules of life. In order to translate human
bioglycosylation into clinical applications, homogeneous samples of oligosaccharides and …

For the stereoselective assembly of bioactive glycans with various functions, 1, 2-cis-O-
glycosylation is one of the most essential issues in synthetic carbohydrate chemistry. The cis …

Shigella is the second most common etiologic pathogen responsible for childhood acute
diarrhea. An anti-Shigella vaccine is still eagerly awaited due to the increasing drug …

The stereoselective introduction of glycosidic bonds is of paramount importance to
oligosaccharide synthesis. Among the various chemical strategies to steer stereoselectivity …

The accessibility to long, branched and complex glycans containing many 1, 2-cis glycosidic
linkages with precise structures remains a challenging task in chemical synthesis. Reported …

We herein present a strain-release glycosylation method employing a rationally designed
ortho-2, 2-dimethoxycarbonylcyclopropylbenzyl (CCPB) thioglycoside donor. The donor is …

Lipoteichoic acids (LTAs) are macroamphiphiles composed of alditol, lipid, phosphate, and
carbohydrate units. Due to their inherent complexity, it is a severe challenge to access LTAs …

A diarylurea-containing phosphine ligand-modulated stereoinvertive O-glycosylation with
primal furanosyl and pyranosyl ortho-alkynylbenzoate (ABz) donors under gold (I) catalysis …

Stereospecific α-glucosylation of primary and secondary OH-group at carbohydrate
acceptors is achieved using glucosyl N-phenyl-trifluoroacetimidate (PTFAI) donor protected …

2′-Deoxynucleosides and analogues play a vital role in drug development, but their
preparation remains a significant challenge. Previous studies have focused on β-2 …