Advances in understanding the human urinary microbiome and its potential role in urinary tract infection

ML Neugent, NV Hulyalkar, VH Nguyen, PE Zimmern… - MBio, 2020 - journals.asm.org
Recent advances in the analysis of microbial communities colonizing the human body have
identified a resident microbial community in the human urinary tract (UT). Compared to many …

Gram‐positive uropathogens, polymicrobial urinary tract infection, and the emerging microbiota of the urinary tract

KA Kline, AL Lewis - Urinary tract infections: molecular …, 2017 - Wiley Online Library
Uncomplicated urinary‐tract infection (UTI) is most common in young, sexually active,
nonpregnant, premenopausal women. Gram‐negative bacteria are isolated from 75% to …

Clinical guidelines for interstitial cystitis/bladder pain syndrome

Y Homma, Y Akiyama, H Tomoe… - … Journal of Urology, 2020 - Wiley Online Library
The clinical guidelines for interstitial cystitis and related symptomatic conditions were
revised by updating our previous guidelines. The current guidelines define interstitial …

The microbiome of the urinary tract—a role beyond infection

SA Whiteside, H Razvi, S Dave, G Reid… - Nature Reviews …, 2015 - nature.com
Urologists rarely need to consider bacteria beyond their role in infectious disease. However,
emerging evidence shows that the microorganisms inhabiting many sites of the body …

Visceral pain

L Grundy, A Erickson, SM Brierley - Annual review of physiology, 2019 - annualreviews.org
Most of us live blissfully unaware of the orchestrated function that our internal organs
conduct. When this peace is interrupted, it is often by routine sensations of hunger and urge …

The urinary microbiome associated with bladder cancer

V Bučević Popović, M Šitum, CET Chow, LS Chan… - Scientific reports, 2018 - nature.com
Recent findings suggest that human microbiome can influence the development of cancer,
but the role of microorganisms in bladder cancer pathogenesis has not been explored yet …

The urinary tract microbiome in health and disease

IM Aragon, B Herrera-Imbroda, MI Queipo-Ortuño… - European urology …, 2018 - Elsevier
Context The urinary tract, previously considered a sterile body niche, has emerged as the
host of an array of bacteria in healthy individuals, revolutionizing the urology research field …

Profiling the urinary microbiota in male patients with bladder cancer in China

P Wu, G Zhang, J Zhao, J Chen, Y Chen… - Frontiers in cellular …, 2018 - frontiersin.org
Mounting evidence indicates that microbiome plays an important role in the development
and progression of cancer. The dogma that urine in healthy individuals must be sterile has …

Interstitial cystitis/bladder pain syndrome: The evolving landscape, animal models and future perspectives

Y Akiyama, Y Luo, PM Hanno… - … Journal of Urology, 2020 - Wiley Online Library
Interstitial cystitis/bladder pain syndrome is a debilitating condition of unknown etiology
characterized by persistent pelvic pain with lower urinary tract symptoms and comprises a …

The microbiome in prostate inflammation and prostate cancer

CM Porter, E Shrestha, LB Peiffer… - Prostate cancer and …, 2018 - nature.com
Background The human microbiome may influence prostate cancer initiation and/or
progression through both direct and indirect interactions. To date, the majority of studies …