ABSTRACT A common, long‐held belief is that metabolic rate drives the rates of various
biological, ecological and evolutionary processes. Although this metabolic pacemaker view …

How organs originate and evolve is a question fundamental to understanding the evolution
of complex multicellular life forms. Vertebrates have a relatively standard body plan with …

The placenta has evolved to support the development of the embryo and fetus during the
different intrauterine periods of life. By necessity, its development must precede that of the …

The co-option of endogenous retroviruses (ERVs) is increasingly recognized as a recurrent
theme in placental biology, which has far-reaching implications for our understanding of …

Reproduction is a central activity for all living organisms but is also associated with a
diversity of costs that are detrimental for survival. Until recently, the cost of cancer as a …

Background Cancer is a common diagnosis in many mammalian species, yet they vary in
their vulnerability to cancer. The factors driving this variation are unknown, but life history …

Senescence patterns are highly variable across the animal kingdom. However, while
empirical evidence of actuarial senescence in vertebrates is accumulating in the wild and …

Objective To investigate the regulatory mechanism of Apelin-13-mediated PI3K/AKT
signaling pathway in the glucose and lipid metabolism of gestational diabetes mellitus …

Among mammals, placental invasion is correlated with vulnerability to malignancy. Animals
with more invasive placentation (for example, humans) are more vulnerable to malignancy …

The oviductal microenvironment is a site for key events that involve gamete maturation,
fertilization and early embryo development. Secretions into the oviductal lumen by either the …