Diabetic retinopathy: Looking forward to 2030

TE Tan, TY Wong - Frontiers in Endocrinology, 2023 - frontiersin.org
Diabetic retinopathy (DR) is the major ocular complication of diabetes mellitus, and is a
problem with significant global health impact. Major advances in diagnostics, technology …

Eye disorders other than diabetic retinopathy in patients with diabetes

S Feldman-Billard, B Dupas - Diabetes & Metabolism, 2021 - Elsevier
Aim While diabetic retinopathy is the most specific complication of chronic hyperglycaemia,
numerous other ocular conditions also can involve the eyes of people with diabetes …

Retinal nerve fiber layer thinning as a novel fingerprint for cardiovascular events: results from the prospective cohorts in UK and China

Y Chen, Y Yuan, S Zhang, S Yang, J Zhang, X Guo… - BMC medicine, 2023 - Springer
Background Retinal structural abnormalities have been found to serve as biomarkers for
cardiovascular disease (CVD). However, the association between retinal nerve fiber layer …

Ganglion cell–inner plexiform layer damage in diabetic patients: 3-year prospective, longitudinal, observational study

HB Lim, YI Shin, MW Lee, H Koo, WH Lee, JY Kim - Scientific reports, 2020 - nature.com
Diabetes is expected to accelerate age-related ganglion cell–inner plexiform layer (GC-IPL)
loss, but there is limited information on the rate of reduction in GC-IPL thicknesses. We …

Deciphering the connection between microvascular damage and neurodegeneration in early diabetic retinopathy

Q Yang, M Yasvoina, A Olvera-Barrios, J Mendes… - Diabetes, 2024 - diabetesjournals.org
Diabetic retinopathy (DR), a common diabetes complication leading to vision loss, presents
early clinical signs linked to retinal vasculature damage, affecting the neural retina at …

[HTML][HTML] A new approach to staging diabetic eye disease: staging of diabetic retinal neurodegeneration and diabetic macular edema

R Channa, RM Wolf, R Simo, M Brigell, P Fort… - Ophthalmology …, 2024 - Elsevier
Topic The goal of this review was to summarize the current level of evidence on biomarkers
to quantify diabetic retinal neurodegeneration (DRN) and diabetic macular edema (DME) …

Assessment of retinal neurodegeneration with spectral-domain optical coherence tomography: a systematic review and meta-analysis

Z Tang, MY Chan, WY Leung, HY Wong, CM Ng… - Eye, 2021 - nature.com
Objectives To comprehensively assess diabetic retinopathy neurodegeneration (DRN) as
quantified by retinal neuronal and axonal layers measured with spectral-domain optical …

Segregation of neuronal and vascular retinal damage in patients with hypertension and diabetes

J Chua, D Wong, AP Yow, B Tan, X Liu… - Annals of the New …, 2024 - Wiley Online Library
This study aimed to examine the impact of diabetes and hypertension on retinal nerve fiber
layer (RNFL) thickness components. Optical coherence tomography (OCT) measurements …

Non-apoptotic programmed cell death as targets for diabetic retinal neurodegeneration

Y Lin, S Ke, W Ye, B **e, Z Huang - Pharmaceuticals, 2024 - mdpi.com
Diabetic retinopathy (DR) remains the leading cause of blindness among the global working-
age population. Emerging evidence underscores the significance of diabetic retinal …

[HTML][HTML] Peripapillary retinal nerve fiber layer and microvasculature in prolonged type 2 diabetes patients without clinical diabetic retinopathy

MW Lee, WH Lee, CK Ryu, YM Lee… - … & visual science, 2021 - tvst.arvojournals.org
Purpose: The purpose of this study to identify the effects of prolonged type 2 diabetes
(T2DM) on the peripapillary retinal nerve fiber layer (pRNFL) and peripapillary …