Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

The blood–brain barrier (BBB) restricts the transport of potential therapeutic moieties to the
brain. Direct targeting the brain via olfactory and trigeminal neural pathways by passing the …

Central nervous system (CNS) disorders (eg, multiple sclerosis, Alzheimer's disease, etc.)
represent a growing public health issue, primarily due to the increased life expectancy and …

The blood–brain barrier (BBB) plays a fundamental role in protecting the brain from toxic
substances and therefore also controls and restricts the entry of therapeutic agents. The …

Oxytocin has garnered considerable interest for its role in social behavior, as well as for the
potential of intranasal administration to treat social difficulties. However, current theoretical …

There is growing interest in the role of the oxytocin system in social cognition and behavior.
Peripheral oxytocin concentrations are regularly used to approximate central concentrations …

Background Current neuroimaging perspectives on a variety of mental disorders emphasize
dysfunction of the amygdala. The neuropeptide oxytocin (OXT), a key mediator in the …

Although small-scale studies have described the effects of oxytocin on social deficits in
autism spectrum disorder (ASD), no large-scale study has been conducted. In this …

One of the major reasons why depressed patients fail their treatment course is the existence
of the blood-brain barrier (BBB), which prevents drugs from being delivered to the central …

In this paper, we analyse the claim that oxytocin is a 'social neuropeptide'. This claim
originated from evidence that oxytocin was instrumental in the initiation of maternal …