Multivalent glycosystems for human lectins
Human lectins are involved in a wide variety of biological processes, both physiological and
pathological, which have attracted the interest of the scientific community working in the …
pathological, which have attracted the interest of the scientific community working in the …
Glycans in drug discovery
P Valverde, A Ardá, NC Reichardt… - …, 2019 - pubs.rsc.org
Glycans are key players in many biological processes. They are essential for protein folding
and stability and act as recognition elements in cell–cell and cell–matrix interactions. Thus …
and stability and act as recognition elements in cell–cell and cell–matrix interactions. Thus …
Glycan-gold nanoparticles as multifunctional probes for multivalent lectin–carbohydrate binding: implications for blocking virus infection and nanoparticle assembly
Multivalent lectin-glycan interactions are widespread in biology and are often exploited by
pathogens to bind and infect host cells. Glycoconjugates can block such interactions and …
pathogens to bind and infect host cells. Glycoconjugates can block such interactions and …
[HTML][HTML] Glycan structures and their interactions with proteins. A NMR view
Highlights•NMR methods are of paramount importance to deduce structure, dynamics and
recognition of complex glycans.•The intrinsic low sensitivity of NMR for studying glycans and …
recognition of complex glycans.•The intrinsic low sensitivity of NMR for studying glycans and …
Binding of the bacterial adhesin FimH to its natural, multivalent high-mannose type glycan targets
Multivalent carbohydrate–lectin interactions at host–pathogen interfaces play a crucial role
in the establishment of infections. Although competitive antagonists that prevent pathogen …
in the establishment of infections. Although competitive antagonists that prevent pathogen …
Recent progress of glycopolymer synthesis for biomedical applications
I Pramudya, H Chung - Biomaterials science, 2019 - pubs.rsc.org
Glycopolymers are an important class of biomaterials which include carbohydrate moieties
in their polymer structure. In addition to biological research on the interactions of …
in their polymer structure. In addition to biological research on the interactions of …
The rise and future of discrete organic–inorganic hybrid nanomaterials
MW Brett, CK Gordon, J Hardy… - ACS Physical Chemistry …, 2022 - ACS Publications
Hybrid nanomaterials (HNs), the combination of organic semiconductor ligands attached to
nanocrystal semiconductor quantum dots, have applications that span a range of practical …
nanocrystal semiconductor quantum dots, have applications that span a range of practical …
Recent advances in nanoparticle-based targeting tactics for antibacterial photodynamic therapy
The rise of antibacterial drug resistance means treatment options are becoming increasingly
limited. We must find ways to tackle these hard-to-treat drug-resistant and biofilm infections …
limited. We must find ways to tackle these hard-to-treat drug-resistant and biofilm infections …
Structure–effect relationship studies of polysaccharides based on receptor–active centres: an alternative view
Polysaccharides are ubiquitous biomolecules found in nature that have attracted research
interest due to their unique nutritional and pharmacological value. Their structural variability …
interest due to their unique nutritional and pharmacological value. Their structural variability …
Polyvalent Glycan Quantum Dots as a Multifunctional Tool for Revealing Thermodynamic, Kinetic, and Structural Details of Multivalent Lectin–Glycan Interactions
J Hooper, Y Liu, D Budhadev, DF Ainaga… - … applied materials & …, 2022 - ACS Publications
Multivalent lectin–glycan interactions (MLGIs) are widespread and vital for biology. Their
binding biophysical and structural details are thus highly valuable, not only for the …
binding biophysical and structural details are thus highly valuable, not only for the …