Experimental and quantitative imaging techniques in interstitial lung disease
Interstitial lung diseases (ILDs) are a heterogeneous group of conditions, with a wide and
complex variety of imaging features. Difficulty in monitoring, treating and exploring novel …
complex variety of imaging features. Difficulty in monitoring, treating and exploring novel …
[HTML][HTML] Novel tracers for molecular imaging of interstitial lung disease: A state of the art review
B Broens, JW Duitman, GJC Zwezerijnen… - Autoimmunity …, 2022 - Elsevier
Interstitial lung disease is an overarching term for a wide range of disorders characterized by
inflammation and/or fibrosis in the lungs. Most prevalent forms, among others, include …
inflammation and/or fibrosis in the lungs. Most prevalent forms, among others, include …
[HTML][HTML] Short-term PM2. 5 exposure induces sustained pulmonary fibrosis development during post-exposure period in rats
B Sun, Y Shi, Y Li, J Jiang, S Liang, J Duan… - Journal of Hazardous …, 2020 - Elsevier
Up to now, while some toxicological studies have identified pulmonary fibrosis immediately
induced by long-term PM 2.5 exposure, there has been no evidence indicating, whether …
induced by long-term PM 2.5 exposure, there has been no evidence indicating, whether …
[18F]FDG PET/CT predicts progression-free survival in patients with idiopathic pulmonary fibrosis
Background Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by an
unpredictable course. Prognostic markers and disease activity markers are needed. The …
unpredictable course. Prognostic markers and disease activity markers are needed. The …
18F-FDG positron emission tomography scanning in systemic sclerosis-associated interstitial lung disease: a pilot study
Background Interstitial lung disease is a common complication of systemic sclerosis (SSc-
ILD), and it remains difficult to accurately predict its course. Progressing ILD could be more …
ILD), and it remains difficult to accurately predict its course. Progressing ILD could be more …
Usefulness of FAPα assessment in bronchoalveolar lavage as a marker of fibrogenesis: results of a preclinical study and first report in patients with idiopathic …
P Lavis, J **itore, G Doumont, A Garabet… - Respiratory …, 2023 - Springer
Background Fibroblast activation protein-α (FAPα) is a marker of activated fibroblasts that
can be selectively targeted by an inhibitor (FAPI) and visualised by PET/CT imaging. We …
can be selectively targeted by an inhibitor (FAPI) and visualised by PET/CT imaging. We …
Quantitative 18F-FDG PET-CT can assess presence and extent of interstitial lung disease in early severe diffuse cutaneous systemic sclerosis
B Broens, EJ Nossent, LJ Meijboom… - Arthritis Research & …, 2024 - Springer
Background This study aimed to assess the quantitative uptake of 18F-FDG PET-CT in the
lungs of patients with early severe diffuse cutaneous systemic sclerosis (SSc) with and …
lungs of patients with early severe diffuse cutaneous systemic sclerosis (SSc) with and …
The quantitative assessment of interstitial lung disease with positron emission tomography scanning in systemic sclerosis patients
DM Peelen, BGJC Zwezerijnen, EJ Nossent… - …, 2020 - academic.oup.com
Objectives The reversibility of interstitial lung disease (ILD) in SSc is difficult to assess by
current diagnostic modalities and there is clinical need for imaging techniques that allow for …
current diagnostic modalities and there is clinical need for imaging techniques that allow for …
[68Ga]FAPI PET for Imaging and Treatment Monitoring in a Preclinical Model of Pulmonary Fibrosis: Comparison to [18F]FDG PET and CT
H Ji, X Song, X Lv, F Shao, Y Long, Y Song, W Song… - Pharmaceuticals, 2024 - mdpi.com
Purpose: This study aimed to evaluate the feasibility of using [68Ga]-fibroblast-activating
protein inhibitor (FAPI) positron emission tomography (PET) imaging for diagnosing …
protein inhibitor (FAPI) positron emission tomography (PET) imaging for diagnosing …
Absence of early metabolic response assessed by 18F-FDG PET/CT after initiation of antifibrotic drugs in IPF patients
B Bondue, A Castiaux, G Van Simaeys, C Mathey… - Respiratory …, 2019 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is characterized by a progressive and
irreversible respiratory failure. Non-invasive markers of disease activity are essential for …
irreversible respiratory failure. Non-invasive markers of disease activity are essential for …