Ependymal cilia: physiology and role in hydrocephalus
W Ji, Z Tang, Y Chen, C Wang, C Tan, J Liao… - Frontiers in Molecular …, 2022 - frontiersin.org
Cerebrospinal fluid (CSF), a colorless liquid that generally circulates from the lateral
ventricles to the third and fourth ventricles, provides essential nutrients for brain homeostasis …
ventricles to the third and fourth ventricles, provides essential nutrients for brain homeostasis …
[HTML][HTML] Mechanisms of cerebrospinal fluid and brain interstitial fluid production
J **ang, Y Hua, G **, RF Keep - Neurobiology of disease, 2023 - Elsevier
Fluid homeostasis is fundamental for brain function with cerebral edema and hydrocephalus
both being major neurological conditions. Fluid movement from blood into brain is one …
both being major neurological conditions. Fluid movement from blood into brain is one …
Lysophosphatidic acid as a CSF lipid in posthemorrhagic hydrocephalus that drives CSF accumulation via TRPV4-induced hyperactivation of NKCC1
TL Toft-Bertelsen, D Barbuskaite, EK Heerfordt… - Fluids and barriers of the …, 2022 - Springer
Background A range of neurological pathologies may lead to secondary hydrocephalus.
Treatment has largely been limited to surgical cerebrospinal fluid (CSF) diversion, as …
Treatment has largely been limited to surgical cerebrospinal fluid (CSF) diversion, as …
Cerebrospinal fluid production by the choroid plexus: a century of barrier research revisited
Cerebrospinal fluid (CSF) envelops the brain and fills the central ventricles. This fluid is
continuously replenished by net fluid extraction from the vasculature by the secretory action …
continuously replenished by net fluid extraction from the vasculature by the secretory action …
Are standing osmotic gradients the main driver of cerebrospinal fluid production? A computational analysis
P Razzaghi Khamesi, V Charitatos… - Fluids and Barriers of …, 2023 - Springer
Background The mechanisms of cerebrospinal fluid (CSF) production by the ventricular
choroid plexus (ChP) have not been fully deciphered. One prominent hypothesized …
choroid plexus (ChP) have not been fully deciphered. One prominent hypothesized …
Elevated CSF inflammatory markers in patients with idiopathic normal pressure hydrocephalus do not promote NKCC1 hyperactivity in rat choroid plexus
SD Lolansen, N Rostgaard, SN Andreassen… - Fluids and Barriers of …, 2021 - Springer
Background Idiopathic normal pressure hydrocephalus (iNPH) is a potentially reversible
neurological condition of unresolved etiology characterized by a clinical triad of symptoms; …
neurological condition of unresolved etiology characterized by a clinical triad of symptoms; …
TRPV4: Cell type-specific activation, regulation and function in the vertebrate eye
L Lapajne, CN Rudzitis, B Cullimore… - Current topics in …, 2022 - Elsevier
The architecture of the vertebrate eye is optimized for efficient delivery and transduction of
photons and processing of signaling cascades downstream from phototransduction. The …
photons and processing of signaling cascades downstream from phototransduction. The …
Targeting choroid plexus epithelium as a novel therapeutic strategy for hydrocephalus
Y Yang, J He, Y Wang, C Wang, C Tan, J Liao… - Journal of …, 2022 - Springer
The choroid plexus is a tissue located in the lateral ventricles of the brain and is composed
mainly of choroid plexus epithelium cells. The main function is currently thought to be the …
mainly of choroid plexus epithelium cells. The main function is currently thought to be the …
Consideration of kinase inhibitors for the treatment of hydrocephalus
BL Blazer-Yost - International Journal of Molecular Sciences, 2023 - mdpi.com
Hydrocephalus is a devastating condition characterized by excess cerebrospinal fluid (CSF)
in the brain. Currently, the only effective treatment is surgical intervention, usually involving …
in the brain. Currently, the only effective treatment is surgical intervention, usually involving …
Following Ussing's legacy: From amphibian models to mammalian kidney and brain
BL Blazer-Yost - American Journal of Physiology-Cell …, 2022 - journals.physiology.org
Professor Hans H. Ussing (1911–2000) was one of the founding members of the field of
epithelial cell biology. He is most famous for the electrophysiological technique that he …
epithelial cell biology. He is most famous for the electrophysiological technique that he …