Type 2 diabetes and cardiovascular disease: have all risk factors the same strength?

I Martín-Timón, C Sevillano-Collantes… - World journal of …, 2014 - pmc.ncbi.nlm.nih.gov
Diabetes mellitus is a chronic condition that occurs when the body cannot produce enough
or effectively use of insulin. Compared with individuals without diabetes, patients with type 2 …

The effect of short-term hyperglycemia on the innate immune system

N Jafar, H Edriss, K Nugent - The American journal of the medical sciences, 2016 - Elsevier
Background Diabetes mellitus increases the susceptibility to infection by altering both the
innate and the adaptive immune systems. Hyperglycemia has been associated with adverse …

Hyperglycemia induces trained immunity in macrophages and their precursors and promotes atherosclerosis

L Edgar, N Akbar, AT Braithwaite, T Krausgruber… - Circulation, 2021 - ahajournals.org
Background: Cardiovascular risk in diabetes remains elevated despite glucose-lowering
therapies. We hypothesized that hyperglycemia induces trained immunity in macrophages …

[HTML][HTML] Impact of polyphenols on inflammatory and oxidative stress factors in diabetes mellitus: nutritional antioxidants and their application in improving antidiabetic …

M Krawczyk, I Burzynska-Pedziwiatr, LA Wozniak… - Biomolecules, 2023 - mdpi.com
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycaemia and
oxidative stress. Oxidative stress plays a crucial role in the development and progression of …

Diabetes-induced male infertility: potential mechanisms and treatment options

R Huang, J Chen, B Guo, C Jiang, W Sun - Molecular medicine, 2024 - Springer
Male infertility is a physiological phenomenon in which a man is unable to impregnate a
fertile woman during a 12-month period of continuous, unprotected sexual intercourse. A …

Therapeutic effects of curcumin in inflammatory and immune‐mediated diseases: A nature‐made jack‐of‐all‐trades?

E Abdollahi, AA Momtazi, TP Johnston… - Journal of cellular …, 2018 - Wiley Online Library
Curcumin is a dietary polyphenol from turmeric with numerous pharmacological activities.
Novel animal and human studies indicate that curcumin can affect different immune cells …

Gestational diabetes mellitus is associated with changes in the concentration and bioactivity of placenta-derived exosomes in maternal circulation across gestation

C Salomon, K Scholz-Romero, S Sarker… - Diabetes, 2016 - diabetesjournals.org
Although there is significant interest in elucidating the role of placenta-derived exosomes
(PdEs) during pregnancy, the exosomal profile in pregnancies complicated by gestational …

Role of inflammatory mechanisms in pathogenesis of type 2 diabetes mellitus

MSH Akash, K Rehman, S Chen - Journal of cellular …, 2013 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) is characterized by progressive β‐cell dysfunctioning and
insulin resistance. This article reviews recent literature with special focus on inflammatory …

Monocyte Chemoattractant Protein 1 (MCP-1) in obesity and diabetes

J Panee - Cytokine, 2012 - Elsevier
Monocyte Chemoattractant Protein-1 (MCP-1) is the first discovered and most extensively
studied CC chemokine, and the amount of studies on its role in the etiologies of obesity-and …

Cytokines induced neutrophil extracellular traps formation: implication for the inflammatory disease condition

RS Keshari, A Jyoti, M Dubey, N Kothari, M Kohli… - PloS one, 2012 - journals.plos.org
Neutrophils (PMNs) and cytokines have a critical role to play in host defense and systemic
inflammatory response syndrome (SIRS). Neutrophil extracellular traps (NETs) have been …