Staphylococcus aureus pathogenesis in diverse host environments

D Balasubramanian, L Harper, B Shopsin… - Pathogens and …, 2017 - academic.oup.com
Staphylococcus aureus is an eminent human pathogen that can colonize the human host
and cause severe life-threatening illnesses. This bacterium can reside in and infect a wide …

[HTML][HTML] Two-component systems of S. aureus: signaling and sensing mechanisms

L Bleul, P Francois, C Wolz - Genes, 2022 - mdpi.com
Genes | Free Full-Text | Two-Component Systems of S. aureus: Signaling and Sensing Mechanisms
Next Article in Journal Genome-Wide Identification, Primary Functional Characterization of the …

Antibacterial properties and mechanism of biopolymer-based films functionalized by CuO/ZnO nanoparticles against Escherichia coli and Staphylococcus aureus

G Guan, L Zhang, J Zhu, H Wu, W Li, Q Sun - Journal of Hazardous …, 2021 - Elsevier
In this study, the nanocomposite film (SA-CS@ CuO/ZnO) composed of sodium alginate (SA)
and chitosan (CS) functionalized by copper oxide nanoparticles (CuONPs) and zinc oxide …

At the crossroads of bacterial metabolism and virulence factor synthesis in Staphylococci

GA Somerville, RA Proctor - Microbiology and Molecular Biology …, 2009 - Am Soc Microbiol
Bacteria live in environments that are subject to rapid changes in the availability of the
nutrients that are necessary to provide energy and biosynthetic intermediates for the …

Bacterial Targets of Antibiotics in Methicillin-Resistant Staphylococcus aureus

H Lade, JS Kim - Antibiotics, 2021 - mdpi.com
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most prevalent bacterial
pathogens and continues to be a leading cause of morbidity and mortality worldwide. MRSA …

Sensory deprivation in Staphylococcus aureus

M Villanueva, B García, J Valle, B Rapún… - Nature …, 2018 - nature.com
Bacteria use two-component systems (TCSs) to sense and respond to environmental
changes. The core genome of the major human pathogen Staphylococcus aureus encodes …

Redox sensing by a Rex‐family repressor is involved in the regulation of anaerobic gene expression in Staphylococcus aureus

M Pagels, S Fuchs, J Pané‐Farré… - Molecular …, 2010 - Wiley Online Library
An alignment of upstream regions of anaerobically induced genes in Staphylococcus aureus
revealed the presence of an inverted repeat, corresponding to Rex binding sites in …

Impaired respiration elicits SrrAB-dependent programmed cell lysis and biofilm formation in Staphylococcus aureus

AA Mashruwala, A Guchte, JM Boyd - Elife, 2017 - elifesciences.org
Biofilms are communities of microorganisms attached to a surface or each other. Biofilm-
associated cells are the etiologic agents of recurrent Staphylococcus aureus infections …

Evolving MRSA: High-level β-lactam resistance in Staphylococcus aureus is associated with RNA Polymerase alterations and fine tuning of gene expression

VV Panchal, C Griffiths, H Mosaei, B Bilyk… - PLoS …, 2020 - journals.plos.org
Most clinical MRSA (methicillin-resistant S. aureus) isolates exhibit low-level β-lactam
resistance (oxacillin MIC 2–4 μg/ml) due to the acquisition of a novel penicillin binding …

[HTML][HTML] A battle for iron: host sequestration and Staphylococcus aureus acquisition

KP Haley, EP Skaar - Microbes and infection, 2012 - Elsevier
The use of iron as an enzymatic cofactor is pervasive in biological systems. Consequently
most living organisms, including pathogenic bacteria, require iron to survive and replicate …